About 15 results found for searched term "CRT" (0.08 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2541 | CRT0044876 | DNA/RNA Synthesis |
| NSC 69877 | ||
| CRT0044876 is a potent and selective APE1 inhibitor with IC50 of ~3 μM. | ||
| M6635 | CRT0066101 dihydrochloride | PKD |
| CRT 0066101 is a potent protein kinase D (PKD) inhibitor. | ||
| M6813 | iCRT 14 | Wnt/beta-catenin |
| iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT), with IC50 of 40.3 nM against Wnt responsive STF16 luciferase. | ||
| M8259 | iCRT3 | Wnt/beta-catenin |
| The key mediator of Wnt signaling is the transcriptional co-activator b-catenin. | ||
| M10809 | CRT0273750 | PDE |
| CRT0273750 is a lead compound of autotaxin (ATX) inhibitors and regulates plasma LPA levels. CRT0273750 can be used in ATX/LPA dependent cancer models. | ||
| M28439 | CRT0066854 | PKC |
| CRT0066854 is a potent and selective atypical PKC isoenzymes inhibitor. CRT0066854 is against full-length (FL) PKCι, PKCζ, and ROCK-II kinases with IC50 values of 132 nM, 639 nM, and 620 nM, respectively. | ||
| M28786 | CRT0105950 | LIM Kinase |
| CRT0105950 is a potent LIMK inhibitor, with IC50s of 0.3 nM and 1 nM for LIMK1 and LIMK2 respectively. CRT0105950 can be used for the research of cancer. | ||
| M28787 | CRT 0105446 | LIM Kinase |
| CRT 0105446 (compound 22d) is a LIMK1 inhibitor, with an IC50 of 8 nM. | ||
| M28962 | iCRT-5 | Wnt/beta-catenin |
| iCRT-5 is a β-catenin-regulated transcription (CRT) inhibitor. iCRT-5 can block Wnt/β-catenin reporter activity and down regulate β-catenin expression. iCRT-5 can be used for the research of multiple myeloma. | ||
| M29437 | CRT0066854 hydrochloride | PKC |
| CRT0066854 hydrochloride is a potent and selective atypical PKCs inhibitor. CRT0066854 is against full-length (FL) PKCι, PKCζ, and ROCK-II kinases with IC50 values of 132 nM, 639 nM, and 620 nM, respectively. | ||
| M30604 | CRTh2 antagonist 2 | Prostaglandin Receptor |
| CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, with an IC50 of ≤10 nM. CRTh2 antagonist 2 can be used in research of androgenic alopecia. | ||
| M43021 | CRT0063465 | Others |
| CRT0063465 is a Ligand of HumanPGK1andStress Sensor DJ1, with theKdof 24 μM ofPGK1. | ||
| M43918 | Recombinant Human Calreticulin Protein (HEK293, C-His) | Cytokines and Growth Factors |
| CRT Protein; CALR | ||
| Calreticulin acts as a main Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. Calreticulin binds Ca2+ ions (a second messenger in signal transduction), rendering it inactive. | ||
| M50438 | CRT | Others |
| CRT, an iron peptide mimic, can bind to apo-transferrin (apo-Tf). | ||
| M62629 | CRTC3 Human Pre-designed siRNA Set | siRNA |
| Human CRTC3 Pre-designed siRNA Set contains three designed siRNAs for CRTC3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 64784 | ||
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