About 6 results found for searched term "CPT2" (0.094 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7738 | CPTH2 | Histone Acetyltransferase |
| CPTH2 is a histone acetyltransferase (HAT) inhibitor modulating the Gcn5 network. | ||
| M8408 | CU-CPT22 | TLR |
| CU-CPT22 is the first probe for the complex between toll-like receptors TLR1 and TLR2. CU-CPT22 shows dose-dependent inhibitory effects blocking Pam3CSK4-induced TLR1/2 activation with an IC50 of 0.58 ± 0.09 µM. | ||
| M25388 | 9-Aminocamptothecin | Topoisomerase |
| 9-amino-CPT; 9-amino-20(S)-camptothecin | ||
| 9-Aminocamptothecin (9-amino-CPT) is a topoisomerase I inhibitor with potent anticancer activity. 9-Aminocamptothecin inhibits PC-3, PC-3M, DU145, and LNCaP cells with IC50 values of 34.1, 10, 6.5, and 8.9 nM, respectively after 96 h exposure. | ||
| M27857 | 8-pCPT-2'-O-Me-cAMP-AM | PKA |
| 8-pCPT-2'-O-Me-cAMP-AM is a cyclic AMP analogue, selectively activates Epac-Rap signaling pathway. 8-pCPT-2'-O-Me-cAMP-AM protects renal function by activating Epac from ischemia injury. 8-pCPT-2'-O-Me-cAMP-AM also stimulates insulin secretion by interaction with PKA pathway. | ||
| M30401 | 8-CPT-2Me-cAMP sodium | Ras |
| 8-CPT-2Me-cAMP sodium is a selective activator of exchange proteins activated by cAMP (Epac), the cAMP sensitive guanine nucleotide exchange factors (GEFs) for the small GTPases Rap1 and Rap2. 8-CPT-2Me-cAMP sodium activates Epac1 (EC50 = 2.2 μM), but not PKA (EC50> 10 μM). 8-CPT-2Me-cAMP sodium stimulates Epac-mediated Ca2+ release in pancreatic β-cells in vitro. | ||
| M41285 | CPT2 | Apoptosis |
| CPT2 (Carnitine palmitoyltransferase 2), an enzyme that participates in fatty acid oxidation, also is a colorectal cancer (CRC) prognostic biomarker. | ||
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