About 9 results found for searched term "C-171" (0.051 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2279 | Citalopram hydrobromide | 5-HT Receptor |
| Celexa; Cipramil; Lu 10-171 | ||
| Citalopram (Celexa, Cipramil) is a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the central nervous system (CNS). | ||
| M2411 | Picropodophyllin (AXL1717) | IGF-1R |
| Picropodophyllotoxin; CAS# 17434-18-3; PPP | ||
| AXL1717 (picropodophyllin, Picropodophyllotoxin, PPP) is a non-competitive, potent, and specific inhibitor of IGF-1Rα/β with IC50 of 1 nM. | ||
| M10839 | JC-171 | NLR |
| JC-171 is a selective inhibitor of NLRP3 inflammasomes that inhibits the release of IL-1β by macrophages induced by LPS/ATP IC50 The value is 8.45 μM. | ||
| M10923 | Giredestrant | Estrogen Receptor |
| GDC-9545; RG6171 | ||
| Giredestrant (GDC-9545, RG6171) is an orally active, selective estrogen receptor degrader (SERD) with best-in-class potential to compete with estradiol in the ER ligand binding domain and induce conformational changes.Giredestrant has antitumor activity. | ||
| M11056 | NSC 617145 | DNA/RNA Synthesis |
| NSC 617145 is a selective werner syndrome helicase (WRN) helicase inhibitor,IC50 The value is 230 nM. NSC 617145 inhibit WRN ATPase and induce double-strand rupture (DSB) and chromosomal abnormalities. NSC 617145 is selective to WRN and superior to BLM, FANCJ, ChlR1, RecQ, and UvrD helicases. | ||
| M20842 | C-171 | STING |
| C-171 is a covalent small-molecule inhibitor of STING. C-171 efficiently inhibits both hsSTING and mmSTING through covalently target the predicted transmembrane cysteine residue 91 and thereby block the activation-induced palmitoylation of STING. | ||
| M27646 | VCP171 | Adenosine Receptor |
| VCP171 is a potent adenosine A1 receptor (A1R) positive allosteric modulator (PAM). VCP171 is effective at decreasing excitatory synaptic currents in Lamina II of neuropathic pain model. VCP171 can be used for researching neuropathic pain. | ||
| M41676 | MC4171 | Histone Acetyltransferase |
| compound 34 | ||
| MC4171 is a first-in-class selective KAT8 inhibitor (IC50=8.1 µM). MC4171 exhibits moderate micromolar antiproliferative activity in different cancer cell lines, including NSCLC and AML, without impacting the viability of nontransformed cells. | ||
| M56159 | CP-481715 | CCR |
| CP-481715 is a potent, reversible and selective CCR1 antagonist with a Kd of 9.2 nM for human CCR1. | ||
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