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 About 18 results found for searched term "BTK" (0.057 seconds)

Cat.No.  Name Target
M8887 Btk inhibitor 2 BTK
Btk inhibitor 2 (BGB-3111) is a Brutons tyrosine kinase (BTK) inhibitor.
M20631 BTK inhibitor 1 (Compound 27) BTK
BTK inhibitor 1 (compound 27) is an inhibitor of BTK with an IC50 of 0.11 nM for Btk and inhibits B cell activation in hWB with an IC50 of 2 nM.
M28101 BTK IN-1 BTK
SNS062 analog
BTK IN-1 (SNS062 analog) is a potent BTK inhibitor, with an IC50 of <100 nM.
M28957 BTK inhibitor 17  BTK
BTK inhibitor 17 is a potent and orally active irreversible BTK inhibitor with an IC50 of 2.1 nM. BTK inhibitor 17 can be used for rheumatoid arthritis research.
M29210 CHMFL-BTK-01  BTK
CHMFL-BTK-01 (compound 9) is a highly selective irreversible BTK inhibitor, with an IC50 of 7 nM. CHMFL-BTK-01 (compound 9) potently inhibited BTK Y223 auto-phosphorylation.
M40697 NX-5948 PROTAC
NX-5948 (BTK-IN-24) is an orally active, blood-brain barrier-penetrating, BTK-targeting degradation agent for the study of B-cell malignancies and autoimmune diseases. NX-5948 induces specific BTK protein degradation by the cereblon E3 ligase (CRBN) complex without degradation of other cereblon neo-substrates. NX-5948 mediates potent anti-inflammatory activity via BTK degradation with resultant inhibition of B cell activation.
M43406 PROTAC BTK Degrader-6 BTK
PROTAC BTK Degrader-6 is a PROTAC BTK degrader (DC50: 3.18 nM.
M43440 PROTAC BTK Degrader-3 PROTAC
PROTAC BTK Degrader-3 is a potent BTK degrader with a DC50 value of 10.9 nM of BTK degradation in Mino cells.
M43472 BTK-IN-26 BTK
BTK-IN-26 is a potent inhibitor of Bruton's tyrosine kinase (BTK) and its C481 mutant, with IC50 values of 0.7 and 0.8 nM for BTK and BTK C481S, respectively.
M43474 BTK-IN-25 BTK
BTK-IN-25 is a potent inhibitor of BTK, and inhibits BTK(C481S) with an IC50 value of 0.77 nM.
M43475 PROTAC BTK Degrader-5 BTK
PROTAC BTK degraders-5is a selective BTK degrader with a DC50 value of 7.0 nM in JeKo-1 cells.
M43477 BTK-IN-27 BTK
BTK-IN-27 is a BTK inhibitor (IC50: 0.2 nM).
M49587 JAK3/BTK-IN-1 JAK
JAK3/BTK-IN-1 is a potent inhibitor of JAK3/BTK.
M49588 JAK3/BTK-IN-2 JAK
JAK3/BTK-IN-2 is a potent inhibitor of JAK3/BTK.
M49589 JAK3/BTK-IN-3 JAK
JAK3/BTK-IN-3 is a potent inhibitor of JAK3/BTK.
M49590 JAK3/BTK-IN-4 JAK
JAK3/BTK-IN-4 is a potent inhibitor of JAK3/BTK.
M49591 JAK3/BTK-IN-5 JAK
JAK3/BTK-IN-5 is a potent inhibitor of JAK3/BTK.
M49783 JAK3/BTK-IN-6 BTK
JAK3/BTK-IN-6 is a potent BTK and JAK3 dual inhibitor, with IC50 values of 0.6 and 0.4 nM, respectively.

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