About 19 results found for searched term "BTK" (0.052 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M8887 | Btk inhibitor 2 | BTK |
| BGB-3111 | ||
| Btk inhibitor 2 (BGB-3111) is a Brutons tyrosine kinase (BTK) inhibitor. | ||
| M20631 | BTK inhibitor 1 (Compound 27) | BTK |
| BTK inhibitor 1 (compound 27) is an inhibitor of BTK with an IC50 of 0.11 nM for Btk and inhibits B cell activation in hWB with an IC50 of 2 nM. | ||
| M28101 | BTK IN-1 | BTK |
| SNS062 analog | ||
| BTK IN-1 (SNS062 analog) is a potent BTK inhibitor, with an IC50 of <100 nM. | ||
| M28957 | BTK inhibitor 17 | BTK |
| BTK inhibitor 17 is a potent and orally active irreversible BTK inhibitor with an IC50 of 2.1 nM. BTK inhibitor 17 can be used for rheumatoid arthritis research. | ||
| M29210 | CHMFL-BTK-01 | BTK |
| CHMFL-BTK-01 (compound 9) is a highly selective irreversible BTK inhibitor, with an IC50 of 7 nM. CHMFL-BTK-01 (compound 9) potently inhibited BTK Y223 auto-phosphorylation. | ||
| M40697 | NX-5948 | PROTAC |
| BTK-IN-24 | ||
| NX-5948 (BTK-IN-24) is an orally active, blood-brain barrier-penetrating, BTK-targeting degradation agent for the study of B-cell malignancies and autoimmune diseases. NX-5948 induces specific BTK protein degradation by the cereblon E3 ligase (CRBN) complex without degradation of other cereblon neo-substrates. NX-5948 mediates potent anti-inflammatory activity via BTK degradation with resultant inhibition of B cell activation. | ||
| M43406 | PROTAC BTK Degrader-6 | BTK |
| PROTAC BTK Degrader-6 is a PROTAC BTK degrader (DC50: 3.18 nM. | ||
| M43440 | PROTAC BTK Degrader-3 | PROTAC |
| PROTAC BTK Degrader-3 is a potent BTK degrader with a DC50 value of 10.9 nM of BTK degradation in Mino cells. | ||
| M43472 | BTK-IN-26 | BTK |
| BTK-IN-26 is a potent inhibitor of Bruton's tyrosine kinase (BTK) and its C481 mutant, with IC50 values of 0.7 and 0.8 nM for BTK and BTK C481S, respectively. | ||
| M43474 | BTK-IN-25 | BTK |
| BTK-IN-25 is a potent inhibitor of BTK, and inhibits BTK(C481S) with an IC50 value of 0.77 nM. | ||
| M43475 | PROTAC BTK Degrader-5 | BTK |
| PROTAC BTK degraders-5is a selective BTK degrader with a DC50 value of 7.0 nM in JeKo-1 cells. | ||
| M43477 | BTK-IN-27 | BTK |
| BTK-IN-27 is a BTK inhibitor (IC50: 0.2 nM). | ||
| M49587 | JAK3/BTK-IN-1 | JAK |
| JAK3/BTK-IN-1 is a potent inhibitor of JAK3/BTK. | ||
| M49588 | JAK3/BTK-IN-2 | JAK |
| JAK3/BTK-IN-2 is a potent inhibitor of JAK3/BTK. | ||
| M49589 | JAK3/BTK-IN-3 | JAK |
| JAK3/BTK-IN-3 is a potent inhibitor of JAK3/BTK. | ||
| M49590 | JAK3/BTK-IN-4 | JAK |
| JAK3/BTK-IN-4 is a potent inhibitor of JAK3/BTK. | ||
| M49591 | JAK3/BTK-IN-5 | JAK |
| JAK3/BTK-IN-5 is a potent inhibitor of JAK3/BTK. | ||
| M49783 | JAK3/BTK-IN-6 | BTK |
| JAK3/BTK-IN-6 is a potent BTK and JAK3 dual inhibitor, with IC50 values of 0.6 and 0.4 nM, respectively. | ||
| M57131 | BTK ligand 1 | Ligands for Target Protein for PROTAC |
| BTK ligand 1 is a ligand targeting Bruton’s tyrosine kinase (Btk). | ||
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