About 4 results found for searched term "Apterin" (0.139 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M44782 | Apterin | NO Synthase |
| Apterin is a natural compound with anti-inflammatory activity. Apterin shows significantly inhibitory activity on NO production in RAW264.7 cells with an IC50 value of 41.8 μM. | ||
| M58137 | L-Sepiapterin | Metabolite/Endogenous Metabolite |
| Sepiapterin | ||
| L-Sepiapterin (Sepiapterin) is a precursor of the endothelial nitric oxide synthase (eNOS) cofactor tetrahydrobiopterin (BH4). L-Sepiapterin improves endothelial dysfunction in small mesenteric arteries from db/db mice, and induces angiogenesis. | ||
| M9744 | QM385 | Others |
| QM385 is a potent sepiapterin reductase (SPR) inhibitor with IC50 of 1.49 nM. | ||
| M28121 | SPR inhibitor 3 | Others |
| SPRi3 | ||
| SPR inhibitor 3 (SPRi3) is a potent sepiapterin reductase (SPR) inhibitor. SPR inhibitor 3 (SPRi3) displays high binding affinity to human SPR in a cell-free assay (IC50=74 nM) and efficiently reduces biopterin levels in a cell-based assay (IC50=5.2 μM). SPR inhibitor 3 (SPRi3) reduces neuropathic and inflammatory pain through a reduction of BH4 levels. | ||
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