About 2 results found for searched term "Acolbifene" (0.133 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M45335 | Acolbifene | Estrogen Receptor |
| EM-652; SCH 57068 | ||
| Acolbifene is an active metabolite of EM800 and an orally active pure anti-estrogen and selective estrogen receptor (ER) antagonist that inhibits estradiol-induced ERα (IC50 = 2 nM) and ERβ (IC50 = 0.4 nM) transcriptional activity and has anticancer activity. | ||
| M45336 | Acolbifene hydrochloride | Estrogen Receptor |
| EM-652 hydrochloride; SCH 57068 hydrochloride | ||
| Acolbifene hydrochloride is an active metabolite of EM800 and an orally available, selective estrogen receptor modulator (SERM) that inhibits estradiol-induced ERα (IC50 = 2 nM) and ERβ (IC50 = 0.4 nM) transcriptional activity, has significant anti-estrogenic effects on the mammary gland and uterus, and has anticancer activity. possesses anticancer activity. | ||
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