About 5 results found for searched term "AUT1" (0.053 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5196 | Spautin-1 | Autophagy |
| Spautin-1 is a potent and specific autophagy inhibitor, and inhibits the deubiquitinating activity of USP10 and USP13 with IC50 of ∼0.6-0.7 μM. | ||
| M10516 | AUT1 | Potassium Channel |
| AUT-1 | ||
| AUT1 is a Kv3 potassium channel modulator which increases whole currents mediated by human Kv3.1b and Kv3.2a channels, with a concomitant leftward shift in the voltage-dependence of activation, while having a less potent effect on hKv3.3 currents. | ||
| M11451 | Autotaxin modulator 1 | PDE |
| Autotaxin Modulator 1 is an Autotaxin (ATX) inhibitor of Autotaxin (ATX). Autotaxin Modulator 1 is expected to be used for demyelination caused by injury or disease, as well as for the study of proliferative diseases such as tumors. | ||
| M28698 | Autotaxin-IN-1 | PDE |
| Autotaxin-IN-1 is a potent autotaxin inhibitor, which has favorable potency (IC50=2.2 nM), PK properties, and a robust PK/PD relationship. Autotaxin-IN-1 is used in treatment of osteoarthritis pain. | ||
| M29557 | Autogramin-1 | Autophagy |
| Autogramin-1 potently inhibits autophagy induced by either starvation (IC50=0.17 μM) or mTORC1 inhibition (Rapamycin; IC50=0.44 μM). | ||
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