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 About 6 results found for searched term "AT791" (0.123 seconds)

Cat.No.  Name Target
M6170 Bedaquiline fumarate Antibiotic
R403323; TMC207 fumarate; R207910 fumarate
Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.
M10784 AT791 Others
AT791 is a potent oral bioavailable inhibitor of TLR7 and TLR9. AT791 inhibits TLR7 and TLR9 signaling for a variety of human and mouse cell types and inhibits DNA-TLR9 interactions in vitro.
M6090 Cilastatin Others
MK0791
Cilastatin (MK0791) is a reversible, competitive renal dehydropeptidase I inhibitor with an IC50 of 0.1 μM.
M10933 GSK3179106 RET
GSK3179106 is an orally active, selective RET kinase inhibitor for human and rat RET IC50 0.4 nM and 0.2 nM, respectively. GSK3179106 has the potential for use in irritable bowel syndrome (IBS) by reducing post-inflammatory and stress-induced visceral hypersensitivity reactions.
M13871 Nelotanserin 5-HT Receptor
APD125
Nelotanserin is a potent 5-HT2A inverse agonist, a moderately potent 5-HT2C partial inverse agonist and a weak 5-HT2B inverse agonist, with IC50s of 1.7, 79, 791 nM in IP accumulation assays, respectively.
M28504 PF-06679142  AMPK
PF-06679142 (Compound 10) is a potent, orally active AMPK activator with an EC50 of 22 nM against α1β1γ1-AMPK. PF-06679142 can be used for diabetic nephropathy research.



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