About 9 results found for searched term "AR-08" (0.053 seconds)
Cat.No. | Name | Target |
---|---|---|
M1879 | XL147 | PI3K |
Pilaralisib; SAR245408 | ||
XL147 (SAR245408) is an orally bioavailable, selective small molecule Class I PI3K kinase family inhibitor. | ||
M6158 | ARQ-087 | FGFR |
Derazantinib | ||
ARQ 087 is a novel, ATP competitive, small molecule, multi-kinase inhibitor with potent in vitro and in vivo activity against FGFR addicted cell lines and tumors. ARQ 087 exhibited IC50 values of 1.8 nM for FGFR2, and 4.5 nM for FGFR1 and 3. | ||
M8221 | Trapidil | Others |
AR-12008 | ||
Terapidil is an antiplatelet compound that partially acts as a competitive inhibitor of phosphodiesterase inhibitors and platelet-derived growth factor (PDGF) receptors. | ||
M14088 | OTX008 | Galectin |
Calixarene 0118; PTX008 | ||
OTX008 is a selective inhibitor of galectin-1. | ||
M19139 | Scarlet 808 | Others |
Scarlet 808 | ||
M21829 | AR-08 | Others |
AR-08 | ||
M25054 | Tusamitamab ravtansine | Drug-Linker Conjugates for ADC |
SAR-408701; HuMAb2-3-SPDB-DM4 | ||
Tusamitamab ravtansine (SAR-408701) is a DM4 anti-CEACAM5 antibody-drug conjugate (ADC). Tusamitamab ravtansine is composed of a humanized monoclonal antibody that binds carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5) and a cytotoxic maytansinoid that selectively targets CEACAM5-expressing tumor cells. | ||
M49407 | Fipaxalparant | LPL Receptor |
SAR-100842; HZN-825 | ||
Fipaxalparant is a potent, orally active and selective LPA1 receptor antagonist for studies related to idiopathic pulmonary fibrosis (IPF). | ||
M57009 | AR-C67085 | Others |
AR-C67085 (PSB 0413; FPL 67085) is a potent platelet P2T receptor antagonist with an pIC50 value of 8.60. |
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