About 19 results found for searched term "API-1" (0.051 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1667 | Sapitinib (AZD8931) | EGFR/HER2 |
| AZD-8931 | ||
| AZD8931 (Sapitinib) is an equipotent, reversible inhibitor of Signaling by EGFR, ERBB2 (HER2), and ERBB3 with IC50 of 4, 3, 4 nM respectively. | ||
| M1884 | Triciribine | Akt |
| API-2, NSC 154020, TCN | ||
| Triciribine (API-2, NSC 154020) is a selective inhibitor of Akt (protein kinase B) signaling with IC50 of 130 nM. | ||
| M3634 | TAPI-1 | Immunology/Inflammation |
| TAPI-1 is an ADAM17/TACE inhibitor that blocks shedding of cytokine receptors with IC50 value of 8.09 microM. | ||
| M6450 | API-1 | Others |
| API-1 is a selective Akt/PKB inhibitor. Antitumor. | ||
| M6451 | Apigenin | Cytochrome P450 (e.g. CYP17) |
| 4',5,7-Trihydroxyflavone; Apigenine; Apigenol; C.I. Natural Yellow 1 | ||
| Apigenin is a competitive CYP2C9 inhibitor with a Ki of 2 μM. | ||
| M8316 | FMP-API-1 | Others |
| FMP-API-1 is an inhibitor of AKAP-PKA interactions in vitro and in cultured cardiac myocytes that activates PKA. | ||
| M9571 | API-1 | Others |
| API-1 is a Pin1 inhibitor with an IC50 of 72.3 nM. API-1 directly and specifically binds to the Pin1 peptidyl-prolyl isomerase (PPIase) domain and potently inhibits Pin1 cis-trans isomerizing activity. | ||
| M10072 | AFN-1252 | Antibiotic |
| API-1252; Debio 1452 | ||
| AFN-1252 (API-1252; Debio-1452) is an enoyl-(acyl-carrier protein) reductase fabl inhibitor. AFN-1252 exhibits typical MIC90 values of ⩽0.015 μg/ml against diverse clinical isolates of S. aureus. | ||
| M16962 | Syringaresinol 4-O-β-D -apiofuranosyl-(1→2)-β-D-glucopyranoside | Lignans |
| Syringaresinol 4-O-β-D -apiofuranosyl-(1→2)-β-D-glucopyranoside | ||
| M17964 | Borneol 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside | Others |
| Borneol 7-O-[β-D-apiofuranosyl-（1→6）]-β-D-glucopyranoside | ||
| M28482 | NaPi2b-IN-1 | Others |
| NaPi2b-IN-1 is a potent and orally active inhibitor of sodium-dependent phosphate transport protein 2b (NaPi2b) with an IC50 of 64 nM. NaPi2b is primarily expressed in the small intestine, lungs, and testes and plays an important role in phosphate homeostasis. NaPi2b-IN-1 has the potential for the research of hyperphosphatemia. | ||
| M44186 | Orcinol 1-O-beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside | Others |
| Orcinol 1-O-beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside | ||
| M44209 | 3-O-[5'''-O-feruloyl-beta-D-apiofuranosyl(1'''->2'')-beta-D-glucopyranosyl] rhamnocitrin | Others |
| 3-O-[5'''-O-feruloyl-beta-D-apiofuranosyl(1'''->2'')-beta-D-glucopyranosyl] rhamnocitrin | ||
| M44211 | Formononetin-8-C-beta-D-apiofuranosyl-(1->6)-O-beta-D-glucopyranoside | Others |
| Formononetin-8-C-beta-D-apiofuranosyl-(1->6)-O-beta-D-glucopyranoside | ||
| M44412 | Apigenin 7-[rhamnosyl-(1->2)-galacturonide] | Others |
| Apigenin 7-[rhamnosyl-(1->2)-galacturonide] | ||
| M44563 | Apigenin-6-C-beta-D-glucopyranosyl-8-C-[alpha-L-rhamnopyranosyl-(1->2)]-beta-glucopyranoside | Others |
| Apigenin-6-C-beta-D-glucopyranosyl-8-C-[alpha-L-rhamnopyranosyl-(1->2)]-beta-glucopyranoside | ||
| M44658 | 2-Methoxyphenyl-4-propylene-1-O-beta-apiofuranosyl-(1-6)-beta-glucopyranoside | Others |
| 2-Methoxyphenyl-4-propylene-1-O-beta-apiofuranosyl-(1-6)-beta-glucopyranoside | ||
| M44996 | Rhamnocitrin 3-apiosyl-(1->2)-glucoside | Others |
| Rhamnocitrin 3-O-β-D-apiofuranosyl(1→2)-β-D-glucopyranoside is a flavonol O-glycoside, isolated from Astragali semen of leguminous plants. | ||
| M57874 | Florbetapir F-18 | Others |
| Florbetapir F-18 | ||
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