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FMP-API-1

Cat. No. M8316

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FMP-API-1 Structure

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Quality Control & Documentation
Biological Activity

FMP-API-1 is an inhibitor of AKAP-PKA interactions in vitro and in cultured cardiac myocytes that activates PKA. Apparently, FMP-API-1 binds to a novel allosteric regulatory site.

Chemical Information
Molecular Weight 230.26
Formula C13H14N2O2
CAS Number 16523-28-7
Solubility (25°C) DMSO: ≥10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Fumiaki Ando. Activation of AQP2 water channels by protein kinase A: therapeutic strategies for congenital nephrogenic diabetes insipidus

[2] Fumiaki Ando, et al. AKAPs-PKA disruptors increase AQP2 activity independently of vasopressin in a model of nephrogenic diabetes insipidus

[3] Xuan Yu, et al. G protein-coupled estrogen receptor 1 mediates relaxation of coronary arteries via cAMP/PKA-dependent activation of MLCP

[4] Frank Christian, et al. Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes

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  Catalog
Abmole Inhibitor Catalog




Keywords: FMP-API-1 supplier, inhibitors, activators

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