About 21 results found for searched term "AP-C2" (0.051 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1884 | Triciribine | Akt |
| API-2, NSC 154020, TCN | ||
| Triciribine (API-2, NSC 154020) is a selective inhibitor of Akt (protein kinase B) signaling with IC50 of 130 nM. | ||
| M1938 | Daptomycin | Antibiotic |
| Cubicin; Dapcin; LY146032 | ||
| Daptomycin is the first member of a new class of bactericidal antibiotics, the cyclic lipopeptides. | ||
| M2080 | Capmatinib (INCB28060) | c-Met |
| INC280; Capmatinib; NVP-INC280 | ||
| Capmatinib (INCB28060) is a novel inhibitor of c-MET kinase with IC50 of 0.13 nM. | ||
| M2403 | MDK83190 | Caspase |
| Apoptosis Activator 2; MDK-83190 | ||
| MDK83190 (Apoptosis Activator 2) strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells. | ||
| M2548 | Cysteamine hydrochloride | Animal Modeling |
| β-MEA Hydrochloride; β-Mercaptoethylamine Hydrochloride; 2-Aminoethanethiol Hydrochloride | ||
| Cysteamine HCl, the hydrochloride form of Cysteamine, is also a transglutaminase 2 (TGM2) inhibitor, which can be used to induce gastrointestinal disorders in a mouse model as well as a duodenal ulcer model. In addition, Cysteamine HCl has the ability to modulate the activity of dopamine neurons in the striatum of awake, freely moving rats by inhibiting the increased dopamine release from amphetamine, and has antioxidant activity. | ||
| M3872 | N-1-naphthylphthalamic acid | Plant growth regulators |
| Naphthalam; NPA; Alanape; ACP 322 | ||
| N-1-Naphthylthalamic acid is a polar auxin transport inhibitor. N-1-Naphthylthalamic acid destroys leaf initiation, KNOX protein regulation and leaf margin formation in maize. | ||
| M4067 | Ginsenoside-Rg2 | NF-κB |
| Chikusetsusaponin I; Panaxoside Rg2; Prosapogenin C2 | ||
| Ginsenoside-Rg2 is one of the major active components of ginseng, acts as a NF-κB inhibitor. | ||
| M4069 | (S)Ginsenoside-Rh1 | PPAR |
| Prosapogenin A2; Sanchinoside B2; Sanchinoside Rh1; Ginsenoside-Rh1 | ||
| Ginsenoside Rh1 (Prosapogenin A2) inhibited the expression of PPAR-γ, TNF-α, IL-6 and IL-1β. | ||
| M6332 | 3-AP | DNA/RNA Synthesis |
| 3-AP; PAN-811; OCX191; NSC663249 | ||
| 3-AP is a ribonucleotide reductase inhibitor; also an iron chelator. | ||
| M6579 | Cerestat | Others |
| Aptiganel; CNS-1102 | ||
| Cerestat (also known as Aptiganel, CNS-1102) is a potent and noncompetitive NMDA receptor antagonist. | ||
| M18243 | Rhaponticin 2''-O-gallate | Others |
| Rhaponticin 2''-O-gallate | ||
| M22479 | Lisaftoclax | Bcl-2 |
| APG-2575; Bcl-2/Bcl-xl inhibitor 1 | ||
| Lisaftoclax (APG-2575) is a dual Bcl-2 and Bcl-xl inhibitor with anti-tumor activity, exhibits IC50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively. | ||
| M25085 | Geptanolimab | PD-1/PD-L1 |
| APL-501; CBT-501; GB-226 | ||
| Geptanolimab (CBT-501) is a humanized IgG4k monoclonal antibody against programmed death-1 (PD-1). Siplizumab inhibits the binding of PD-L1/L2 to PD-1 through a competitive action. Siplizumab can be used in research of cancer. | ||
| M28704 | FM4-64 | Fluorescent Dye |
| SynaptoRedTM C2 | ||
| FM4-64 is a very lipophilic, water-soluble styrene dyes, can specifically bind to cell membranes and inner membrane organelles to produce fluorescence. FM4-64 is widely used in endocytic and exospic membrane structure markers. | ||
| M39700 | Capecitabine-2',3'-cyclic carbonate | Others |
| Capecitabine-2',3'-cyclic carbonate (Compd 5a) is a 5'-deoxy-5-fluorocytidine derivative with anticancer activity. | ||
| M41299 | Apoptosis inducer 12 | Apoptosis |
| Apoptosis inducer 12 is an apoptosis inducer that induces apoptosis through the mitochondrial pathway. | ||
| M42607 | AP-C2 | Serine/Threonine Protease |
| AP-C2 is a potent guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2. | ||
| M43156 | Rapamycin analog-2 | Others |
| Rapamycin analog-2 is a Rapamycin analog. | ||
| M43836 | Recombinant Human AP2 Gamma/TFAP2C Protein (E. coli, His Tag) | Cytokines and Growth Factors |
| hAP-2g Protein; transcription factor AP-2 gamma | ||
| TFAP2C, also known as AP2-GAMMA, is a member of the activating protein 2 family of transcription factors. TFAP2C may be prognostic indicators for breast tumors. | ||
| M44563 | Apigenin-6-C-beta-D-glucopyranosyl-8-C-[alpha-L-rhamnopyranosyl-(1->2)]-beta-glucopyranoside | Others |
| Apigenin-6-C-beta-D-glucopyranosyl-8-C-[alpha-L-rhamnopyranosyl-(1->2)]-beta-glucopyranoside | ||
| M54771 | Carbacyclin | Prostaglandin Receptor |
| Carbaprostacyclin; Carba-PGI2 | ||
| Carbacyclin is a PGI2 analogue, acts as a prostacyclin (PGI2) receptor agonist and vasodilator, and potently inhibits platelet aggregation. | ||
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