About 26 results found for searched term "AP-C2" (0.08 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1884 | Triciribine | Akt |
| API-2, NSC 154020, TCN | ||
| Triciribine (API-2, NSC 154020) is a selective inhibitor of Akt (protein kinase B) signaling with IC50 of 130 nM. | ||
| M1938 | Daptomycin | Antibiotic |
| Cubicin; Dapcin; LY146032 | ||
| Daptomycin is the first member of a new class of bactericidal antibiotics, the cyclic lipopeptides. | ||
| M2080 | Capmatinib (INCB28060) | c-Met |
| INC280; Capmatinib; NVP-INC280 | ||
| Capmatinib (INCB28060) is a novel inhibitor of c-MET kinase with IC50 of 0.13 nM. | ||
| M2403 | MDK83190 | Caspase |
| Apoptosis Activator 2; MDK-83190 | ||
| MDK83190 (Apoptosis Activator 2) strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells. | ||
| M2548 | Cysteamine hydrochloride | Animal Modeling |
| β-MEA Hydrochloride; β-Mercaptoethylamine Hydrochloride; 2-Aminoethanethiol Hydrochloride | ||
| Cysteamine HCl, the hydrochloride form of Cysteamine, is also a transglutaminase 2 (TGM2) inhibitor, which can be used to induce gastrointestinal disorders in a mouse model as well as a duodenal ulcer model. In addition, Cysteamine HCl has the ability to modulate the activity of dopamine neurons in the striatum of awake, freely moving rats by inhibiting the increased dopamine release from amphetamine, and has antioxidant activity. | ||
| M3872 | N-1-naphthylphthalamic acid | Plant growth regulators |
| Naphthalam; NPA; Alanape; ACP 322 | ||
| N-1-Naphthylthalamic acid is a polar auxin transport inhibitor. N-1-Naphthylthalamic acid destroys leaf initiation, KNOX protein regulation and leaf margin formation in maize. N-1-naphthylphthalic acid (NPA) is an inhibitor of IAA polar transport, it blocks auxin transport by competing with IAA for binding sites on AtPIN3. | ||
| M4067 | Ginsenoside-Rg2 | NF-κB |
| Chikusetsusaponin I; Panaxoside Rg2; Prosapogenin C2 | ||
| Ginsenoside-Rg2 is one of the major active components of ginseng, acts as a NF-κB inhibitor. | ||
| M4069 | (S)Ginsenoside-Rh1 | PPAR |
| Prosapogenin A2; Sanchinoside B2; Sanchinoside Rh1; Ginsenoside-Rh1 | ||
| Ginsenoside Rh1 (Prosapogenin A2) inhibited the expression of PPAR-γ, TNF-α, IL-6 and IL-1β. | ||
| M6579 | Cerestat | Others |
| Aptiganel; CNS-1102 | ||
| Cerestat (also known as Aptiganel, CNS-1102) is a potent and noncompetitive NMDA receptor antagonist. | ||
| M9600 | 2-Aminoethyl diphenylborinate | Calcium Channel |
| 2-APB; diphenylboric acid-2-aminoethyl ester; DPBA | ||
| 2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of IP3R, and regulate IP3-induced calcium release. 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca2+ (SOC) channel and activates some TRP channels (V1, V2 and V3). | ||
| M18243 | Rhaponticin 2''-O-gallate | Others |
| Rhaponticin 2''-O-gallate | ||
| M22479 | Lisaftoclax | Bcl-2 |
| APG-2575; Bcl-2/Bcl-xl inhibitor 1 | ||
| Lisaftoclax (APG-2575) is a dual Bcl-2 and Bcl-xl inhibitor with anti-tumor activity, exhibits IC50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively. | ||
| M25085 | Geptanolimab | PD-1/PD-L1 |
| APL-501; CBT-501; GB-226 | ||
| Geptanolimab (CBT-501) is a humanized IgG4k monoclonal antibody against programmed death-1 (PD-1). Siplizumab inhibits the binding of PD-L1/L2 to PD-1 through a competitive action. Siplizumab can be used in research of cancer. | ||
| M28704 | FM4-64 | Fluorescent Dye |
| SynaptoRedTM C2 | ||
| FM4-64 is a very lipophilic, water-soluble styrene dyes, can specifically bind to cell membranes and inner membrane organelles to produce fluorescence. FM4-64 is widely used in endocytic and exospic membrane structure markers. | ||
| M39700 | Capecitabine-2',3'-cyclic carbonate | Others |
| Capecitabine-2',3'-cyclic carbonate (Compd 5a) is a 5'-deoxy-5-fluorocytidine derivative with anticancer activity. | ||
| M41299 | Apoptosis inducer 12 | Apoptosis |
| Apoptosis inducer 12 is an apoptosis inducer that induces apoptosis through the mitochondrial pathway. | ||
| M42607 | AP-C2 | Serine/Threonine Protease |
| AP-C2 is a potent guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2. | ||
| M43156 | Rapamycin analog-2 | Others |
| Rapamycin analog-2 is a Rapamycin analog. | ||
| M43836 | Recombinant Human AP2 Gamma/TFAP2C Protein (E. coli, His Tag) | Cytokines and Growth Factors |
| hAP-2g Protein; transcription factor AP-2 gamma | ||
| TFAP2C, also known as AP2-GAMMA, is a member of the activating protein 2 family of transcription factors. TFAP2C may be prognostic indicators for breast tumors. | ||
| M44563 | Apigenin-6-C-beta-D-glucopyranosyl-8-C-[alpha-L-rhamnopyranosyl-(1->2)]-beta-glucopyranoside | Others |
| Apigenin-6-C-beta-D-glucopyranosyl-8-C-[alpha-L-rhamnopyranosyl-(1->2)]-beta-glucopyranoside | ||
| M54771 | Carbacyclin | Prostaglandin Receptor |
| Carbaprostacyclin; Carba-PGI2 | ||
| Carbacyclin is a PGI2 analogue, acts as a prostacyclin (PGI2) receptor agonist and vasodilator, and potently inhibits platelet aggregation. | ||
| M59330 | Recombinant Human MAPK14 Protein (E. coli, N-His) | Enzymes & Regulators |
| MAP kinase p38 alpha; MAP kinase 14; CSBP; MXI2; SAPK2A | ||
| MAPK14 is an important serine/threonine kinase in the MAP kinase pathway. It can respond to stimuli such as cytokines or stress and directly activate transcription factors. In this cascade, p38 MAPK each phosphorylates approximately 200 to 300 substrates, including the downstream kinases RPS6KA5/MSK1 and RPS6KA4/MSK2, which are critical for immediate early gene induction. | ||
| M61333 | Apoc2 Mouse Pre-designed siRNA Set | siRNA |
| Mouse Apoc2 Pre-designed siRNA Set contains three designed siRNAs for Apoc2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 11813 | ||
| M63596 | SNAPC2 Human Pre-designed siRNA Set | siRNA |
| Human SNAPC2 Pre-designed siRNA Set contains three designed siRNAs for SNAPC2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 6618 | ||
| M63744 | APOC2 Human Pre-designed siRNA Set | siRNA |
| Human APOC2 Pre-designed siRNA Set contains three designed siRNAs for APOC2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 344 | ||
| M64332 | SAPCD2 Human Pre-designed siRNA Set | siRNA |
| Human SAPCD2 Pre-designed siRNA Set contains three designed siRNAs for SAPCD2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 89958 | ||
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