About 9 results found for searched term "A-366" (0.061 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3477 | Imidapril hydrochloride | ACE |
| TA-6366 | ||
| Imidapril hydrochloride is a angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension. Imidapril hydrochloride inhibits lipopolysaccharide-induced phosphorylation of c-Jun, MKK4 and JNK in monocytes, and downregulates the production of specific inflammatory factors such as TNF-α and IP-10, thereby exerting anti-inflammatory activity. | ||
| M6446 | APC 366 | Others |
| APC 366 is a tryptase inhibitor. | ||
| M8529 | A-366 | Histone Methyltransferase |
| A366 | ||
| A-366 is a potent and highly selective peptide-competitive inhibitor of histone methyltransferase G9a, with IC50s of 3.3 nM and 38 nM for G9a and GLP, respectively, and is more than 1,000-fold selective for G9a and GLP over 21 other methyltransferases. A-366 is also a potent inhibitor of Spindlin1-H3K4me3 interaction (IC50=182.6 nM).A-366 shows high affinity for human H3R (Ki=17 nM) and exhibits subtype selectivity between subpopulations of the histaminergic and dopaminergic receptor families. It can be used for induction and maintenance of pluripotent stem cells in mice. | ||
| M8920 | BDA-366 | Bcl-2 |
| BDA-366 is a small molecule antagonist that specifically binds the BCL2 BH4 domain, and has the ability to convert anti-apoptotic BCL2 into a pro-apoptotic death molecule. | ||
| M20094 | WAY-321366 | Others |
| WAY-321366 is a abelson tyrosine kinase inhibitor | ||
| M29279 | Ganfeborole | Antibiotic |
| GSK656 free base; GSK3036656 free base; GSK070 free base | ||
| Ganfeborole (GSK656 free base) is a potent, selective and orally active inhibitor of M. tuberculosis leucyl-tRNA synthetase, with an IC50 of 0.20 μM. Ganfeborole can be used for the research of tuberculosis. | ||
| M51151 | Influenza A NP (366-374) | Others |
| Influenza A NP (366-374) is a biological active peptide. | ||
| M53453 | Influenza A NP(366-374) Strain A/PR/8/35 | Anti-infection |
| Influenza A NP(366-374) Strain A/PR/8/35 is an H2-Db-restricted epitope from Influenza A/PR/8/35 nucleoprotein. | ||
| M55839 | AN3661 | Parasite |
| AN3661, a potent antimalarial lead compound, targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue subunit 3 (PfCPSF3). | ||
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