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APC 366

Cat. No. M6446

All AbMole products are for research use only, cannot be used for human consumption.

APC 366 Structure

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Quality Control & Documentation
Biological Activity

APC 366 is a selective inhibitor of mast cell tryptase (Ki = 7.1 μM) that inhibits tryptase-induced histamine release from human tonsil and lung cells. Reduces airway inflammation and blocks postchallenge airway hyperresponsiveness in vivo.

Chemical Information
Molecular Weight 440.5
Formula C22H28N6O4
CAS Number 158921-85-8
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Fabbro, et al. Anticancer Drug Des. PKC412 - a protein kinase inhibitor with a broad therapeutic potential.

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Keywords: APC 366 supplier, inhibitors, activators

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