About 5 results found for searched term "94-20-2" (0.059 seconds)
Cat.No. | Name | Target |
---|---|---|
M2511 | Chlorpropamide | Sodium Channel |
Chlorpropamide is a sulfonylurea compound used to study non-insulin-dependent diabetes mellitus (NIDDM). | ||
M8232 | BTZO-1 | Others |
BTZO-1 is a suppressor of cardiomyocyte apoptosis presumably by activation of antioxidant response element (ARE)-mediated gene expression. | ||
M21366 | AGN194204 | RAR/RXR |
IRX4204; NRX194204; VTP 194204 | ||
AGN194204 (IRX4204) is inactive against RAR and is an orally active and selective RXR agonist with Kd values of 0.4 nM, 3.6 nM and 3.8 nM for RXRα, RXRβ and RXRγ, respectively, and EC50s of 0.2 nM, 0.8 nM and 0.08 nM. AGN194204 has anti-inflammatory and anti-cancer effects. | ||
M29809 | NU223612 | PROTAC |
NU223612 is a potent PROTAC (PROTACs) that degrades indoleamine 2,3-dioxygenase 1 (IDO1) (Indoleamine 2,3-Dioxygenase (IDO)) with a Kd of 640 nM. NU223612 potently degrades the IDO1 protein through CRBN-mediated proteasomal degradation. NU223612 is bound to CRBN with an affinity of 290 nM. NU223612 can cross the blood-brain barrier (BBB). | ||
M41869 | Resomelagon acetate | Melanocortin Receptor |
Resomelagon (AP1189) acetate is a potent, orally active melanocortin receptor (MR) agonist about MC1 and MC3. |
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