About 2 results found for searched term "853400-76-7" (0.257 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M21112 | Trofinetide acetate | Peptides |
| NNZ-2566 acetate | ||
| Trofinetide (NNZ-2566) acetate is a novel analogue of the amino-terminal tripeptide of IGF-1, stimulates synaptic maturation, inhibits the production of inflammatory cytokines and the hyperactivation of microglia and astrocytes, and increases the amount of available IGF-1 that can bind to the IGF-1 receptor. Sequence: G-α-Me-Pro-E. | ||
| M45379 | Trofinetide | Peptides |
| NNZ-2566 | ||
| Trofinetide, a water-soluble analog of glycine-proline-glutamic acid (GPE), uses the unnatural amino acid 2-methylproline in place of the proline found in the natural compound, and works by enhancing synaptic activity, restoring synaptic structure, inhibiting the effects of inflammatory compounds in the brain, increasing antioxidant responses, reducing injury-induced cell death, and increasing central IGF-1 presence. It has neuroprotective activity and can be used in studies related to Rett syndrome. | ||
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