About 7 results found for searched term "65-61-2" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4647 | Phorbol 12-myristate 13-acetate | PKC |
| PMA, TPA, 12-O-tetradecanoyl-phorbol-13-acetate; 12,13-tetradecanoyl phorbol acetate | ||
| Phorbol 12-myristate 13-acetate (PMA) is a dual SphK and protein kinase C (PKC) activator, increases the intracellular Ca2+ concentration ([Ca2+]i) in a dose-dependent manner, with an EC50 of 11.7 nM. | ||
| M6088 | LY2409881 | IκB/IKK |
| LY2409881 is a novel selective inhibitor of IKK2 with IC50 of 30 nM; IC50 for IKK1 and other common kinases is at least one log higher. | ||
| M6404 | Acridine Orange hydrochloride | Fluorescent Dye |
| Acridine Orange hydrochloride is a nucleic acid binding dye. | ||
| M17328 | Amaronol B | Phenols |
| Amaronol B | ||
| M4138 | Deucravacitinib (BMS-986165) | JAK |
| BMS986165 | ||
| Deucravacitinib (BMS-986165) is a first-in-class, selective, orally bioavailable inhibitor of TYK2 transitions.Deucravacitinib selectively binds the TYK2 pseudokinase (JH2) structural domain with an IC50 of 1.0 nM and a Ki value of 0.02 nM. Deucravacitinib (BMS-986165) blocks receptor-mediated Tyk2 activation by stably regulating the JH2 structural domain. deucravacitinib also inhibits the IL-12/23 and type I IFN pathways. deucravacitinib may be used in psoriasis research. | ||
| M7261 | SB 265610 | CXCR |
| SB 265610 is a potent CXCR2 antagonist. | ||
| M29617 | MAGL-IN-6 | MAGL |
| MAGL-IN-6 is a potent MAGL inhibitor with an IC50 of 4.71 nM. MAGL-IN-6 can be used for neurological disorders research (WO2020065613A1; example 234). | ||
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