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SB 265610

Cat. No. M7261

All AbMole products are for research use only, cannot be used for human consumption.

SB 265610 Structure
Size Price Availability Quantity
5mg USD 150  USD150 In stock
10mg USD 240  USD240 In stock
25mg USD 480  USD480 In stock
50mg USD 750  USD750 In stock
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Quality Control & Documentation
Biological Activity

SB 265610 is a potent CXCR2 antagonist that inhibits CINC-1-mediated but not C5a-mediated Ca2+ mobilization (IC50 values are 3.4 and 6800 nM respectively). Inhibits CINC-induced chemotaxis and attenuates neutrophil accumulation in inflammatory lung injury in vivo.

Chemical Information
Molecular Weight 357.16
Formula C14H9BrN6O
CAS Number 211096-49-0
Form Solid
Solubility (25°C) DMSO 35.72 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Keïta, et al. Eur J Pharmacol. Antinociceptive effect of a κ-opioid receptor agonist that minimally crosses the blood-brain barrier (ICI 204448) in a rat model of mononeuropathy.

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Keywords: SB 265610 supplier, CXCR, inhibitors, activators

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