About 11 results found for searched term "64-99-3" (0.054 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2587 | JW 55 | PARP |
| JW 55 is an inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). JW55 decreased auto-PARsylation of TNKS1/2 in vitro with IC50 values of 1.9 uM and 830 nM respectively. | ||
| M4577 | Segetalin-B | Peptides |
| Segetalin-B is an orally active cyclopentapeptide found in Vaccaria segetalis, possesses estrogen-like activity. Segetalin B promotes mineralization of ovariectomized rat-derived bone marrow mesenchymal stem cells (BMSCs) in vitro and increases the level of osteocalcin, BMP-2, ALP, and SIRT1 activity. | ||
| M5267 | E7449 | PARP |
| Stenoparib; 2X-121; MGI25036 | ||
| E7449 is an orally bioavailable, brain penetrable, small molecule dual inhibitor of PARP1/2 that also inhibits PARP5a/5b, otherwise known as tankyrase1 and 2 (TNKS1/2), important regulators of canonical Wnt/β-catenin signaling. It has IC50 values of 1.0 and 1.2 nM for PARP1 and 2, respectively. | ||
| M6491 | BAY 58-2667 hydrochloride | Guanylate Cyclase |
| BAY 58-2667 hydrochloride is a potent soluble guanylyl cyclase (sGC) activator. | ||
| M25612 | RMC-6291 | Ras |
| M11427 | RM-018 | Ras |
| INDEX NAME NOT YET ASSIGNED | ||
| RM-018 is an inhibitor of the active state of KRASG12C. Rm-018 retains the ability to bind and inhibit KRASG12C/Y96D. Rm-018 combines with GTP-bound to activate the [" RAS(ON) "] state of KRASG12C. | ||
| M22229 | Etimizol | Others |
| Etimizol | ||
| M43389 | FD274 | PI3K |
| FD274 is a highly potent PI3K/mTOR dual inhibitor with IC50s of 0.65 nM, 1.57 nM, 0.65 nM, 0.42 nM, and 2.03 nM against PI3Kα/β/γ/δ and mTOR, respectively. | ||
| M43765 | Calyxin B | Others |
| Calyxin B can be extracted from the seeds of Alpinia blepharocalyx. | ||
| M50772 | CFP10 (71–85) | Others |
| CFP10 (71–85) is a biological active peptide. | ||
| M53136 | (Des-Pyr1, Des-Gly10, D-Leu6, Pro-NHEt9)-LHRH | LHRH/GnRH |
| (Des-Pyr1,Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. | ||
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