About 14 results found for searched term "60-81-1" (0.057 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2030 | Apremilast | PDE |
| CC-10004 | ||
| Apremilast is a novel, orally available small molecule inhibitor of PDE4 with IC50 of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC50 of 104 nM. | ||
| M3801 | TCS 21311 | JAK |
| TCS 21311 is a potent JAK3 inhibitor with IC50 of 8 nM. | ||
| M4606 | Phloridzin | SGLT |
| Floridzin; NSC 2833 | ||
| Phloridzin is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor. | ||
| M20610 | AMG319 | PI3K |
| AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2. | ||
| M20715 | CS-2660 (JNJ-38158471) | VEGFR/PDGFR |
| CS-2660 (JNJ-38158471) is a well tolerated, orally available, highly selective VEGFR-2 inhibitor with IC50 of 40 nM. CS-2660 (JNJ-38158471) also inhibits closely related tyrosine kinases such as Ret and Kit with IC50 of 180 nM and 500 nM，while it has no significant activity (>1 microM) against VEGFR-1 and VEGFR-3. | ||
| M24726 | Birtamimab | Amyloid |
| NEOD001 | ||
| Birtamimab (NEOD001) is an investigational monoclonal antibody that specifically and selectively target and clear the amyloid. Birtamimab can be used for the research of light chain amyloidosis. | ||
| M24727 | Blontuvetmab | Others |
| AT 004; VT 007 | ||
| Blontuvetmab (AT 004)is a caninized CD20 monoclonal antibody. Blontuvetmab can be used for the research of Canine B-cell lymphoma. | ||
| M24728 | Tamtuvetmab | Others |
| AT-005; AT005 | ||
| Tamtuvetmab (AT-005) is a caninised blontuvetmab against CD52. Tamtuvetmab increases progression-free survival (PFS), exhibits in vivo efficacy in dogs with naïve T-cell lymphoma (LSA). Tamtuvetmab has been approved by veterinary. | ||
| M43296 | 5-FAM-Pro-Leu-OH | Others |
| 5-FAM-Pro-Leu-OH is a biological active peptide. | ||
| M50925 | Tyrosyltryptophan | Others |
| Tyrosyltryptophan is a polypeptide that can be found by peptide screening. | ||
| M53734 | Z-D-Ser-OH | Amino Acid Derivatives |
| Z-D-Ser-OH is a serine derivative. | ||
| M55942 | bio-THZ1 | CDK |
| bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7. | ||
| M57450 | 1-(6-Chloropyridin-2-yl)cyclopropanecarboxylic acid | Others |
| 1-(6-Chloropyridin-2-yl)cyclopropanecarboxylic acid | ||
| M57865 | 1-(6-chloropyridin-2-yl)cyclopropane-1-carboxylic acid | Others |
| 1-(6-chloropyridin-2-yl)cyclopropane-1-carboxylic acid | ||
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