About 6 results found for searched term "58-28-6" (0.052 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6664 | Desipramine hydrochloride | Dopamine Receptor |
| Desipramine hydrochloride is an inhibitor of norepinephrine transporter (NET), 5-HT transporter (SERT) and dopamine transporter (DAT) with Kis of 4, 61 and 78,720 nM, respectively. | ||
| M9274 | SMI-16a | Pim |
| PIM1/2 Kinase Inhibitor VI | ||
| SMI-16a is a potent, cell-permeable, ATP-competitive inhibitor of Pim-1/2 kinases with IC50s of 150 nM and 20 nM against Pim-1 and Pim-2, respectively. | ||
| M29717 | XT2 | Others |
| XT2 is a potent, orally active, and selective inhibitor of NF-κB-inducing kinase (NIK) with an IC50 of 9.1 nM. XT2 suppresses CCl4-induced upregulation of ALT, a key biomarker of acute liver injury. XT2 also decreases immune cell infiltration into the injured liver tissue. XT2 has the potential for the research of liver inflammatory diseases. | ||
| M29784 | DS45500853 | Estrogen Receptor |
| DS45500853 is an estrogen-related receptor α (ERRα) agonist. DS45500853 inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD; 1.2 μM) with an IC50 value of 0.80 μM. DS45500853 can be used for the research of metabolic disorders, including type 2 diabetes mellitus (T2DM). | ||
| M45094 | (S)-Subasumstat | Others |
| (S)-TAK-981 | ||
| (S)-Subasumstat is the inactive isomer of Subasumstat and serves as a control compound in experiments.Subasumstat is a first-in-class, selective inhibitor of the SUMOylation enzymatic reaction with potential immune-activating and antitumor activity. | ||
| M57813 | S- PF 04995274 | Others |
| S- PF 04995274 | ||
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