About 22 results found for searched term "50-50-0" (0.211 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2683 | Estradiol Benzoate | Animal Modeling |
| β-estradiol-3-benzoate | ||
| Estradiol Benzoate is an estrogen analog and an estrogen receptor (ER) agonist that binds to human, murine, and chicken ERα with an IC50 in the range of 22-28 nM.In addition, Estradiol Benzoate can be used in animal disease models (e.g., rat bacterial vaginitis model, rat prostatitis model, etc.). Construct. | ||
| M3569 | AST-1306 (TsOH) | EGFR/HER2 |
| AST-6; Allitinib tosylate | ||
| AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, also effective in mutation EGFR T790M/L858R, more potent to ErbB2-overexpressing cells, 3000-fold selective for ErbB family than other kinases, | ||
| M5222 | Mertansine | Microtubule |
| DM1, Maytansinoid | ||
| Mertansine is a tubulin inhibitor，inhibits the assembly of microtubules by binding to tubulin, with a linker structure can create an antibody-drug conjugate (ADC). *The compound is unstable in solutions, freshly prepared is recommended | ||
| M9966 | PF-06446846 hydrochloride | PCSK9 |
| PF-06446846 HCl | ||
| PF-06446846 hydrochloride is a selective orally active PCSK9 inhibitor that appears to act by causing the ribosome to stall when synthesizing PCSK9. | ||
| M15105 | SR15006 | Others |
| SR15006 is an inhibitor of Kruppel-like factor 5 (KLF5) (IC50 = 41.6 nM in DLD-1 CRC cells). | ||
| M20357 | WAY-352563 | CDK |
| WAY-352563 is a CDK9 inhibitor. | ||
| M22455 | PLGA lactide:glycolide (50:50) MW 120000 | Others |
| Poly(D,L-lactide-co-glycolide) is a synthetic amino acid that has been used to deliver macromolecular therapeutics. | ||
| M29680 | SR18662 | KLF |
| SR18662 is a potent inhibitor of Krüppel-like factor five (KLF5) with an IC50 of 4.4 nM and an analogue of ML264 with improved inhibitory potency against colorectal cancer cells. SR18662 can be used for the study of colorectal cancer. | ||
| M29681 | Bexirestrant | Estrogen Receptor |
| Bexirestrant is an orally active ER-α degrader. Bexirestrant can be used for the research of antiestrogen, antineoplastic. | ||
| M29682 | Elenestinib | c-Kit |
| BLU-263 | ||
| Elenestinib (BLU-263) is a potent and orally active tyrosine kinase inhibitor. Elenestinib has the potential for the research of systemic mastocytosis (SM). | ||
| M41325 | Bim BH3 | Bcl-2 |
| Bim BH3 is a biological active peptide. | ||
| M41326 | Bik BH3 | Bcl-2 |
| Bik BH3 is a biological active peptide. | ||
| M42526 | Noxa A BH3 | NADPH Oxidase |
| Noxa A BH3 is a biological active peptide. | ||
| M42527 | Noxa B BH3 | NADPH Oxidase |
| Noxa B BH3 is a biological active peptide. | ||
| M42945 | Decyclohexanamine-Exatecan | Others |
| Decyclohexanamine-Exatecan is a Camptothecin derivative, compound a, extracted from patent WO2020219287 A1. | ||
| M43963 | PLGA lactide:glycolide (50:50) (MW 90000) | Solvents & Excipients |
| Poly(DL-lactide-co-glycolide) | ||
| PLGA lactide:glycolide (50:50) (MW 90000) Poly(D,L-propylidene-CO-ethylidene glycolide) is a synthetic amino acid that can be used for macromolecular delivery. | ||
| M49679 | STAT3-IN-11 | STAT |
| STAT3-IN-11 is a selective STAT3 inhibitor that inhibits the phosphorylation of STAT3 at site pTyr705. | ||
| M49797 | m-PEG-OH(MW5000) | PROTAC Linker |
| mPEG-Hydroxy(MW5000); Polyethylene glycol monomethyl ether(MW5000) | ||
| m-PEG-OH is a PROTAC linker and belongs to the PEG class. It can be used to synthesize PROTAC molecules. | ||
| M50622 | Brevinin-1E | Others |
| Brevinin-1E is an antimicrobial peptide derived from the skin secretions of Rana esculenta. | ||
| M53411 | Bid BH3 (80-99) | Bcl-2 |
| Bid BH3 (80-99) is a biological active peptide. | ||
| M53412 | Bad BH3 (mouse) | Bcl-2 |
| Bad BH3 (mouse) is a biological active peptide. | ||
| M54726 | Chitosan (MW 150000) | Cell Transfection |
| Deacetylated chitin (MW 150000); Poly(D-glucosamine) (MW 150000) | ||
| Chitosan (MW 150000) is a polycationic linear polysaccharide derived from chitin with a molecular weight of 150000.Chitosan is non-toxic, hypoallergenic, biocompatible, biodegradable, and possesses anti-tumor, anti-bacterial, anti-fungal, and anti-oxidant activities.Chitosan can be used in studies related to drug delivery and cell transfection. | ||
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