About 6 results found for searched term "351-50-8" (0.478 seconds)
Cat.No. | Name | Target |
---|---|---|
M22432 | D-Histidine | Mitochondrial Related |
D-Histidine | ||
M3730 | CNX-1351 | PI3K |
Cnx-1351 is an effective selective PI3Kα inhibitor with an IC50 of 6.8 nM. | ||
M7536 | BMS-935177 | BTK |
BMS-935177 is a potent, reversible Bruton's Tyrosine Kinase (BTK) inhibitor with an IC50 value of 2.8 nM and demonstrates good kinase selectivity. It is more potent against BTK than other kinase, including the other Tec family kinases (TEC, BMX, ITK, and TXK) over which the compound is between 5- and 67-fold selective. | ||
M20749 | TP0463518 | HIF |
TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with Ki of 5.3 nM for human PHD2. TP0463518 inhibits human PHD1, human PHD3 and monkey PHD2 with IC50 of 18 nM, 63 nM and 22 nM, respectively. | ||
M21654 | BTRX-335140 | Opioid Receptor |
CYM-53093 | ||
BTRX-335140 is a selective and orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively. Navacaprant endows with favorable in vitro ADMET and in vivo pharmacokinetic profiles and medication-like duration of action in rats. | ||
M41796 | PD 135158 | Cholecystokinin Receptor |
PD 135158 (CAM 1028) is a selective CCKB receptor antagonist with an IC50 of 2.8 nM against mouse cortex CCKB. |
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