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D-Histidine

Cat. No. M22432
D-Histidine Structure
Size Price Availability Quantity
1g USD 35  USD35 In stock
5g USD 45  USD45 In stock
25g USD 90  USD90 In stock
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Quality Control & Documentation
Biological Activity

D-Histidine

Chemical Information
Molecular Weight 155.15
Formula C6H9N3O2
CAS Number 351-50-8
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Zhenyang Zhang, et al. Biofouling. Synergistic effects of D-arginine, D-methionine and D-histidine against Porphyromonas gingivalis biofilms

[2] Daniel Ouedraogo, et al. Arch Biochem Biophys. Amine oxidation by d-arginine dehydrogenase in Pseudomonas aeruginosa

[3] Masahiro Kawahara, et al. Metallomics. D-histidine and L-histidine attenuate zinc-induced neuronal death in GT1-7 cells

[4] Mali Illangasekare, et al. RNA. Chiral histidine selection by D-ribose RNA

[5] K Hecht, et al. J Bacteriol. D-histidine utilization in Salmonella typhimurium is controlled by the leucine-responsive regulatory protein (Lrp)

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Keywords: D-Histidine supplier, Mitochondrial Related, inhibitors, activators


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