About 3 results found for searched term "303-54-8" (0.134 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28057 | JTE-952 | CSF-1R (c-Fms) |
| JTE-952 is a potent, oral active and selective Type II inhibitor of colony stimulating factor-1 receptor (CSF-1R or cFMS, type III receptor tyrosine kinase), with IC50 values of 13 nM and 261 nM for CSF1R and TrkA , respectively. Effective against a mouse collagen-induced model of arthritis. | ||
| M30662 | Treprostinil diethanolamine | Prostaglandin Receptor |
| UT-15C | ||
| Treprostinil (UT-15C) diethanolamine is a potent EP2, DP1 and IP agonist with Ki values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1, EP4, EP3 and FP, respectively. Treprostinil (UT-15C) diethanolamine increases upregulation of cAMP toward maintaining homeostasis within the vasculature. Treprostinil (UT-15C) diethanolamine can result in vasodilatation of human pulmonary arteries. | ||
| M42655 | Depramine | AChR/AChE |
| Depramine (GP 31406) is a tricyclic antidepressant with pharmacologically activity. | ||
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