Free shipping on all orders over $ 500

Treprostinil diethanolamine

Cat. No. M30662

All AbMole products are for research use only, cannot be used for human consumption.

Treprostinil diethanolamine Structure
Synonym:

UT-15C

Size Price Availability Quantity
5mg USD 550  USD550 In stock
10mg USD 800  USD800 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Treprostinil (UT-15C) diethanolamine is a potent EP2, DP1 and IP agonist with Ki values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1, EP4, EP3 and FP, respectively. Treprostinil (UT-15C) diethanolamine increases upregulation of cAMP toward maintaining homeostasis within the vasculature. Treprostinil (UT-15C) diethanolamine can result in vasodilatation of human pulmonary arteries.

Chemical Information
Molecular Weight 495.65
Formula C27H45NO7
CAS Number 830354-48-8
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Steven D Nathan, et al. Lancet Respir Med. Inhaled treprostinil and forced vital capacity in patients with interstitial lung disease and associated pulmonary hypertension: a post-hoc analysis of the INCREASE study

[2] Aaron Waxman, et al. N Engl J Med. Inhaled Treprostinil in Pulmonary Hypertension Due to Interstitial Lung Disease

[3] R James White, et al. Am J Respir Crit Care Med. Combination Therapy with Oral Treprostinil for Pulmonary Arterial Hypertension. A Double-Blind Placebo-controlled Clinical Trial

[4] No authors listed. Treprostinil

[5] Jeremy Feldman, et al. Expert Rev Clin Pharmacol. Oral treprostinil diethanolamine for pulmonary arterial hypertension

Related Prostaglandin Receptor Products
Prostaglandin D2

Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals. PGD2 plays a protective role by suppressing inflammation.

Tafluprost acid

Tafluprost acid (AFP-172) is a selective prostanoid FP receptor agonist. Tafluprost acid shows a high affinity for human prostanoid FP receptor with Ki and EC50 values of 0.4 nM and 0.53 nM, respectively. Tafluprost acid has 126 times weaker binding affinity for prostanoid EP3 receptor (IC50=67 nM) than for the prostanoid FP receptor.

TG8-260 

TG8-260 is a second-generation EP2 antagonist developed to alleviate the pathology of central nervous system and peripheral diseases driven by inflammation.

Camonagrel 

Camonagrel is a compound that has inhibitory effects on Prostaglandin E2.

BAY 73-1449 

BAY 73-1449 is a selective antagonist of prostacyclin receptor (IP), with high potency (IC50 of less than 0.1 nM) in cAMP assays in Human HEL cells and rat DRG.

  Catalog
Abmole Inhibitor Catalog




Keywords: Treprostinil diethanolamine, UT-15C supplier, Prostaglandin Receptor, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.