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ZW4864 

Cat. No. M29742

All AbMole products are for research use only, cannot be used for human consumption.

ZW4864  Structure

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Quality Control & Documentation
Biological Activity

ZW4864 is an orally active and selective β catenin/B-Cell lymphoma 9 protein−protein interaction (β catenin/BCL9 PPI) inhibitor. ZW4864 inhibits β catenin/BCL9 PPI with a Ki value of 0.76 μM and an IC50 value of 0.87 μM.

Chemical Information
Molecular Weight 607.19
Formula C33H43ClN6O3
CAS Number 2632259-93-7
Form Solid
Solubility (25°C) DMSO 41.67 mg/mL (ultrasonic and warming and heat to 60°C)
Storage 4°C, dry, sealed
References

[1] Zhen Wang, et al. ACS Med Chem Lett. New ZW4864 Derivatives as Small-Molecule Inhibitors for the β-Catenin/BCL9 Protein-Protein Interaction

[2] Zhen Wang, et al. J Med Chem. Discovery of an Orally Bioavailable Small-Molecule Inhibitor for the β-Catenin/B-Cell Lymphoma 9 Protein-Protein Interaction

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  Catalog
Abmole Inhibitor Catalog




Keywords: ZW4864  supplier, Wnt/beta-catenin, inhibitors, activators

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