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Z-Asp-CH2-DCB is an irreversible, cell permeable broad-spectrum caspase inhibitor, with IC50 values of 1.1 and 4.1 μM for caspase-3 and caspase-6 respectively. Z-Asp-CH2-DCB inhibits hypoxia-induced apoptosis.
Z-Asp-CH2-DCB shows anti-ischemic effects in vivo.
| Molecular Weight | 454.26 |
| Formula | C20H17Cl2NO7 |
| CAS Number | 153088-73-4 |
| Solubility (25°C) | DMSO: 10 mM |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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