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Y16

Cat. No. M14058

All AbMole products are for research use only, cannot be used for human consumption.

Y16 Structure
Size Price Availability Quantity
5mg USD 85  USD85 In stock
10mg USD 140  USD140 In stock
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Biological Activity

Y16 is a specific inhibitor of Leukemia-associated Rho guanine nucleotide exchange factor (LARG) with a Kd value of 76 nM. Y16 is active in blocking the interaction of LARG and related G-protein-coupled Rho GEFs with RhoA. Y16 shows no detectable effect on other diffuse B-cell lymphoma (Dbl) family Rho GEFs, Rho effectors, or a RhoGAP.

Chemical Information
Molecular Weight 384.43
CAS Number 429653-73-6
Solubility (25°C) DMSO 25 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Solairaj Dhanasekaran, et al. Trehalose supplementation enhanced the biocontrol efficiency of Sporidiobolus pararoseus Y16 through increased oxidative stress tolerance and altered transcriptome

[2] Samina Hamid, et al. Correction to: Bacillus subtilis Y16 and biogas slurry enhanced potassium to sodium ratio and physiology of sunflower (Helianthus annuus L.) to mitigate salt stress

[3] Wei-Chiao Chiu, et al. Small chemical compounds Y16 and Rhosin can inhibit calcium sensitization pathway in vascular smooth muscle cells of spontaneously hypertensive rats

[4] Samina Hamid, et al. Bacillus subtilis Y16 and biogas slurry enhanced potassium to sodium ratio and physiology of sunflower (Helianthus annuus L.) to mitigate salt stress

[5] Xiaofei Huang, et al. Ammonium removal by a novel oligotrophic Acinetobacter sp. Y16 capable of heterotrophic nitrification-aerobic denitrification at low temperature

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Keywords: Y16 supplier, Ras, inhibitors, activators

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