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WKYMVM TFA

Cat. No. M10147

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WKYMVM TFA Structure
Synonym:

CAS# 187986-17-0

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Biological Activity

WKYMVM TFA is a potent N-formyl peptide receptor (FPR1) and FPRL1/2 agonist. WKYMVM TFA activates several leukocyte effector functions such as chemotaxis, mobilization of complement receptor-3, and activation of the NADPH oxidase.

Chemical Information
Molecular Weight 970.13
Formula C43H62F3N9O9S2
CAS Number 1313730-09-4
Solubility (25°C) Water
Storage -20°C, protect from light, sealed
References

[1] T Christophe, et al. Scand J Immunol. Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1/LXA4R, is not affected by lipoxin A4

[2] T Christophe, et al. J Biol Chem. The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates neutrophils through FPRL1/lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2

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N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA) is a formyl peptide receptor (FPR) agonist.

WKYMVM-NH2 TFA

WKYMVM-NH2 TFA is a potent N-formyl peptide receptor (FPR1) and FPRL1/2 agonist, also activates several leukocyte effector functions.

{Boc}-Phe-Leu-Phe-Leu-Phe

{Boc}-Phe-Leu-Phe-Leu-Phe ({Boc}-FLFLF) is a formyl peptide receptor (FPR) family antagonist that preferentially inhibits activity triggered through the formyl peptide receptor.

WKYMVM

WKYMVM is a potent N-formyl peptide receptor (FPR1) and FPRL1/2 agonist, also activates several leukocyte effector functions such as chemotaxis, mobilization of complement receptor-3, and activation of the NADPH oxidase.

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Keywords: WKYMVM TFA, CAS# 187986-17-0 supplier, FPR, inhibitors, activators

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