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PBP10 TFA salt

Cat. No. M9845

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PBP10 TFA salt Structure
Size Price Availability Quantity
1mg USD 200  USD200 In stock
5mg USD 440  USD440 In stock
10mg USD 640  USD640 In stock
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Quality Control & Documentation
Biological Activity

PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects. PBP10 is also a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1.

Sequence: RhB-Gln-Arg-Leu-Phe-Gln-Val-Lys-Gly-Arg-Arg-OH

Chemical Information
Molecular Weight 1827.08
Formula C86H128F3N24O17
CAS Number 794466-43-6 (free base)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ewelina Piktel, et al. J Nanobiotechnology. Inhibition of inflammatory response in human keratinocytes by magnetic nanoparticles functionalized with PBP10 peptide derived from the PIP2-binding site of human plasma gelsolin

[2] Huamei Fu, et al. BMC Cell Biol. The two neutrophil members of the formylpeptide receptor family activate the NADPH-oxidase through signals that differ in sensitivity to a gelsolin derived phosphoinositide-binding peptide

[3] C C Cunningham, et al. J Biol Chem. Cell permeant polyphosphoinositide-binding peptides that block cell motility and actin assembly

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Keywords: PBP10 TFA salt supplier, FPR, inhibitors, activators

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