About 27 results found for searched term "FPR" (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3236 | Cefprozil hydrate | Others |
| Cefprozil hydrate (Cefzil) is a second-generation cephalosporin type antibiotic. | ||
| M7370 | TC-FPR 43 | FPR |
| TC-FPR 43 is a potent FPR2 agonist. | ||
| M25195 | Efprezimod alfa | Others |
| Efprezimod alfa is an active peptide. Efprezimod alfa can be used for various biochemical studies. | ||
| M30924 | Cefprozil | Antibiotic |
| Cefprozil (Cefzil) is a second-generation cephalosporin type antibiotic. | ||
| M6514 | BML 111 | Others |
| BML 111 is a fPR2 (lipoxin A 4 receptor) agonist. | ||
| M7176 | Quin C1 | Others |
| Quin C1 is a potent and selective FPR2 agonist. | ||
| M7618 | AG-09/1 | FPR |
| AG-09/1 is a selective formyl peptide receptor 1 (FPR1) agonist; it activates chemotaxis in human neutrophils. | ||
| M9875 | ACT-389949 | FPR |
| ACT389949 | ||
| ACT-389949 is a first-in-class, potent, selective formyl peptide receptor 2/lipoprotein A4 receptor (FPR2)/(ALX) agonist with an EC50 value of 3 nM for FPR2/ALX entry into monocytes.Additionally, ACT-389949 is an excellent tool compound for in vitro and in vivo to further analyze FPR2-regulated activity, which could be used in the development of next-generation FPR signaling-regulated anti-inflammatory therapies. | ||
| M10147 | WKYMVM TFA | FPR |
| CAS# 187986-17-0 | ||
| WKYMVM TFA is a potent N-formyl peptide receptor (FPR1) and FPRL1/2 agonist. | ||
| M10468 | N-Formyl-Met-Leu-Phe | FPR |
| fMLP | ||
| N-Formyl-Met-Leu-Phe (fMLP) is a chemotactic peptide and a specific ligand of N-formyl peptide receptor (FPR), which can inhibit TNF-alpha secretion. | ||
| M10451 | WRW4 | FPR |
| TRP-ARG-TRP-TRP-TRP-TRP-NH2 | ||
| WRW4 is a selective antagonist of formyl peptide receptor 1 (FPR1) signaling, it inhibits WKYMVm binding to FPR1 (IC50 = 0.23 μM). | ||
| M10538 | N-Boc-Phe-Leu-Phe-Leu-Phe (Boc2) | FPR |
| Boc2; Boc-FLFLF | ||
| N-Boc-Phe-Leu-Phe-Leu-Phe (Boc2) is a nonselective N-formyl peptide receptor (FPR) antagonist. | ||
| M10897 | Randialic acid B | FPR |
| Randialic acid B is a triterpenoid compound that is a formyl peptide receptor 1 (FPR1) antagonist. Randialic acid B blocks FPR1 in human neutrophils and reduces psoriasis-like inflammation in vivo. | ||
| M14663 | Boc-MLF TFA | FPR |
| Boc-Met-Leu-Phe-OH (TFA) | ||
| Boc-MLF (TFA) is a peptide, used as a specific formyl peptide receptor (FPR) antagonist, also inhibits the signaling through formyl peptide receptor like 1 (FPRL1) at higher concentrations. | ||
| M21272 | BMS-986235 | FPR |
| LAR-1219 | ||
| BMS-986235/LAR-1219 is an FPR1-sparing FPR2-selective agonist designed to help address chronic inflammation/promote wound healing to prevent serious complications such as heart failure. | ||
| M29125 | PD 168368 | Bombesin Receptor |
| PD 168368 is a potent, competitive, and selective neuromedin B receptor (NMB-R) antagonist with the Ki of 15–45 nM. PD 168368 is neuromedin B receptor (NMBR; IC50=96 nM) / gastrin-releasing peptide receptor (GRPR IC50=3500 nM) antagonist. PD 168368 also is a mixed FPR1/FPR2/FPR3 agonist with EC50s of 0.57, 0.24, and 2.7 nM, respectively. | ||
| M29126 | PD176252 | Bombesin Receptor |
| PD176252 is a potent antagonist of neuromedin-B preferring (BB1) and gastrin-releasing peptide-preferring (BB2) receptor with Kis of 0.17 nM and 1 nM for human BB1 and BB2 receptors, and 0.66 nM, 16 nM for Rat BB1 and BB2 receptors, respectively; PD176252 is also an agonist of N-Formyl peptide receptor1/2 (FPR1/FPR2), with EC50s of 0.31 and 0.66 μM in HL-60 cells. | ||
| M31296 | Trp-Lys-Tyr-Met-Val-Met-NH2 | FPR |
| WKYMVm | ||
| Trp-Lys-Tyr-Met-Val-Met-NH2 (WKYMVm) is a synthetic peptide that is also a specific agonist for formyl peptide-like receptor 1 (FPRL1). | ||
| M31297 | WKYMVM acetate | FPR |
| WKYMVM acetate is a potent agonist of the N-formyl peptide receptors FPR1 and FPRL1/2, and also activates a number of leukocyte effector functions such as chemotaxis, activation of complement receptor-3 and NADPH oxidase. | ||
| M53183 | MMK1 | FPR |
| MMK1 is a potent and selective human formyl peptide receptor like-1 (FPRL-1/FPR2) agonist with EC50s of <2 nM and >10000 nM for FPRL-1 and FPR1, respectively. | ||
| M53184 | N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA | FPR |
| N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA) is a formyl peptide receptor (FPR) agonist. | ||
| M53185 | N-Formyl-Met-Leu-Phe-Lys | FPR |
| N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively. | ||
| M53908 | WKYMVM | FPR |
| WKYMVM is a potent N-formyl peptide receptor (FPR1) and FPRL1/2 agonist, also activates several leukocyte effector functions such as chemotaxis, mobilization of complement receptor-3, and activation of the NADPH oxidase. | ||
| M53962 | {Boc}-Phe-Leu-Phe-Leu-Phe | FPR |
| {Boc}-Phe-Leu-Phe-Leu-Phe ({Boc}-FLFLF) is a formyl peptide receptor (FPR) family antagonist that preferentially inhibits activity triggered through the formyl peptide receptor. | ||
| M54247 | WKYMVM-NH2 TFA | FPR |
| WKYMVM-NH2 TFA is a potent N-formyl peptide receptor (FPR1) and FPRL1/2 agonist, also activates several leukocyte effector functions. | ||
| M54317 | N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys | FPR |
| N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA) is a formyl peptide receptor (FPR) agonist. | ||
| M54382 | Ac9-25 | FPR |
| Ac9-25, a N-terminal peptide of Annexin I, acts as a formyl peptide receptor (FPR) agonist and activates the neutrophil NADPH oxidase through FPR. | ||
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