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VU6004256 

Cat. No. M29105

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VU6004256  Structure

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Quality Control & Documentation
Biological Activity

VU6004256 is a potent and selective M1 muscarinic positive allosteric modulator (PAM) with an EC50 value of 155 nM. VU6004256 has the potential for the research of schizophrenia.

Chemical Information
Molecular Weight 465.5
Formula C25H25F2N5O2
CAS Number 2011034-33-4
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Elham Khajehali, et al. Biochem Pharmacol. Probing the binding site of novel selective positive allosteric modulators at the M1 muscarinic acetylcholine receptor

[2] Michael D Grannan, et al. ACS Chem Neurosci. Prefrontal Cortex-Mediated Impairments in a Genetic Model of NMDA Receptor Hypofunction Are Reversed by the Novel M1 PAM VU6004256

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Keywords: VU6004256  supplier, AChR/AChE, inhibitors, activators

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