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The behavior of vinflunine in routine clinical practice resembles that of the pivotal phase III randomized study. Vinflunine(VFL)-EPR combination is feasible with manageable toxicity. The antitumour activity was promising and supports further evaluation. It underscores a critical function for VFL in cell-cell adhesions of epithelial bladder tumour cells, suggesting a novel molecular mechanism by which VFL may impact upon EMT and metastasis.
| Molecular Weight | 816.93 |
| Formula | C45H54F2N4O8 |
| CAS Number | 162652-95-1 |
| Solubility (25°C) | DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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