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Vevorisertib

Cat. No. M28378

All AbMole products are for research use only, cannot be used for human consumption.

Vevorisertib Structure
Synonym:

ARQ 751

Price and Availability

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Quality Control & Documentation
Biological Activity

Vevorisertib (ARQ 751) is an orally active, potent and selective pan-AKT serine/threonine kinase inhibitor against AKT1 (IC50=0.55 nM), AKT2 (IC50=0.81 nM), and AKT3 (IC50=1.31 nM). Vevorisertib, as a single agent or in combination with other anti-cancer agents, can be used for the research of solid tumors with PIK3CA / AKT / PTEN mutations.

Chemical Information
Molecular Weight 586.73
Formula C35H38N8O
CAS Number 1416775-46-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Shubham Pant, et al. Cancer. Phase 1b study of pan-AKT inhibitor vevorisertib alone or with paclitaxel or fulvestrant in PIK3CA/AKT/PTEN-mutated advanced solid tumors

[2] Keerthi Kurma, et al. Int J Mol Sci. Effect of Novel AKT Inhibitor Vevorisertib as Single Agent and in Combination with Sorafenib on Hepatocellular Carcinoma in a Cirrhotic Rat Model

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  Catalog
Abmole Inhibitor Catalog




Keywords: Vevorisertib, ARQ 751 supplier, Akt, inhibitors, activators

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