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Vanillic acid

Cat. No. M18902
Vanillic acid  Structure
Size Price Availability Quantity
100mg USD 30  USD30 In stock
500mg USD 50  USD50 In stock
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Quality Control & Documentation
Biological Activity

Vanillic acid

Chemical Information
CAS Number 121-34-6
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Ronnie J M Lubbers, et al. Microb Cell Fact. Vanillic acid and methoxyhydroquinone production from guaiacyl units and related aromatic compounds using Aspergillus niger cell factories

[2] Huan Liu, et al. J Fish Dis. Vanillic acid combats Vibrio alginolyticus by cell membrane damage and biofilm reduction

[3] Sepideh Shekari, et al. Curr Pharm Des. Vanillic Acid and Non-Alcoholic Fatty Liver Disease: A Focus on AMPK in Adipose and Liver Tissues

[4] Ifedolapo M Oke, et al. J Pharm Pharmacol. Vanillic acid-Zn(II) complex: a novel complex with antihyperglycaemic and anti-oxidative activity

[5] Pedro H S Cesar, et al. Biotechnol Appl Biochem. Vanillic acid as phospholipase A 2 and proteases inhibitor: In vitro and computational analyses

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