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Purpurogallin is a naturally phenol extracted from the plants of Quercus spp, has potent xanthine oxidase (XO) inhibitory activity with an IC50 of 0.2 µM. Purpurogallin has antioxidant and anti-inflammatory effects. Purpurogallin (50 or 100 µM; 7 or 25 hours; BV2 murine microglial cells) treatment attenuates the production of pro-inflammatory cytokines, including interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) by suppressing their mRNA and protein expression in LPS-stimulated BV2 microglial cells.
| Molecular Weight | 220.18 |
| Formula | C11H8O5 |
| CAS Number | 569-77-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage | -20°C, sealed |
| Related Xanthine Oxidase Products |
|---|
| Topiroxostat
Topiroxostat (FYX-051) is a novel and potent xanthine oxidoreductase (XOR) inhibitor with IC50 value of 5.3 nM. |
| Broussoflavonol F
Broussoflavonol F has xanthine oxidase inhibitory activity. |
| Vanillic acid
Vanillic acid inhibits NF-κB activation. Vanillic acid has anti-inflammatory, antibacterial, and chemopreventive effects. |
| 8-Azaadenine
8-Azaadenine |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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