Free shipping on all orders over $ 500

Broussoflavonol F

Cat. No. M11115
Broussoflavonol F  Structure
Size Price Availability Quantity
5mg USD 700  USD700 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Broussoflavonol F has xanthine oxidase inhibitory activity.

Chemical Information
Molecular Weight 422.47
Formula C25H26O6
CAS Number 162558-94-3
Solubility (25°C) N/A
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Apriliana Cahya Khayrani, et al. J King Saud Univ Sci. Evaluating the potency of Sulawesi propolis compounds as ACE-2 inhibitors through molecular docking for COVID-19 drug discovery preliminary study

[2] Muhamad Sahlan, et al. J King Saud Univ Sci. Molecular interaction analysis of Sulawesi propolis compounds with SARS-CoV-2 main protease as preliminary study for COVID-19 drug discovery

[3] Le Tran Nguyen Vu, et al. Nat Prod Res. Prenylated flavonoids and other constituents from Macaranga indica

[4] Peter A Segun, et al. Fitoterapia. Bioassay-guided isolation and structure elucidation of cytotoxic stilbenes and flavonols from the leaves of Macaranga barteri

[5] Ryo Miyata, et al. J Nat Prod. Propolis Components from Stingless Bees Collected on South Sulawesi, Indonesia, and Their Xanthine Oxidase Inhibitory Activity

Related Xanthine Oxidase Products
H-Tyr-Phe-OH

H-Tyr-Phe-OH (L-Tyrosyl-L-phenylalanine) is an orally active inhibitor of Angiotensin converting enzyme (ACE), with an inhibiton rate of 48% at 50 μM.

TEI-6469

TEI-6469 is a xanthine oxidase (XO) inhibitor that may be used in studies related to gout.

Phytic acid dodecasodium hydrate

Phytic acid (Inositol hexaphosphate) dodecasodium hydrate is a phosphorus storage compound of seeds and cereal grains.

Ellagic acid-4-O-beta-D-xylopyranoside

Ellagic acid 4-O-β-D-xylopyranoside is a natural ellagitannin with antimicrobial activity. Ellagic acid 4-O-β-D-xylopyranoside is an xanthine oxidase inhibitor with an 50 of 2.1 μg/mL.

Protosappanin A dimethyl acetal

Protosappanin A dimethyl acetal is a homoisoflavonoid.

  Catalog
Abmole Inhibitor Catalog




Keywords: Broussoflavonol F supplier, Xanthine Oxidase, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.