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Ubretid

Cat. No. M28633

All AbMole products are for research use only, cannot be used for human consumption.

Ubretid Structure
Synonym:

Distigmine dibromide

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Quality Control & Documentation
Biological Activity

Ubretid is a potent inhibitor of plasma cholinesterase. Ubretid therefore delays the hydrolysis of suxamethonium and prolongs its action, similar to the effects shown by other anticholinesterase agents, such as pyridostigmine and donepezil. Ubretid has the potential for the research of urinary retention prolongs the effect of suxamethonium. Ubretid is commonly prescribed for the research of myasthenia gravis and for difficulty in emptying the bladder.

Chemical Information
Molecular Weight 576.32
Formula C22H32Br2N4O4
CAS Number 15876-67-2
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage 4°C, dry, sealed
References

[1] Shiroh Isono, et al. J Anesth. Ubretid (distigmine bromide) taken to treat urinary retention prolongs the effect of suxamethonium

[2] H P Breuel, et al. Int J Clin Pharmacol Ther Toxicol. Inhibition of acetylcholinesterase by distigmine bromide (Ubretid)

[3] No authors listed. Drug Ther Bull. Distigmine (ubretid)

[4] J Yeo, et al. Med J Aust. A further report on the effect of distigmine bromide (Ubretid) on the neurogenic bladder

[5] T Inada, et al. Hinyokika Kiyo. [Use of "Ubretid" in the field of urology]

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Keywords: Ubretid, Distigmine dibromide supplier, AChR/AChE, inhibitors, activators

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