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Trolox

Cat. No. M7434

All AbMole products are for research use only, cannot be used for human consumption.

Trolox Structure
Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
500mg USD 40  USD40 In stock
1g USD 50  USD50 In stock
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Quality Control & Documentation
Biological Activity

Trolox is a vitamin E analogue that has powerful antioxidant properties. Trolox is a scavenger of ROS. Trolox is also a ferroptosis inhibitor. Trolox has shown to protect mammalian cells from oxidative damage. Trolox is effective in preventing myocyte necrosis in cell culture studies and in a canine model of two hours of left anterior descending coronary artery (LAD) occlusion followed by four hours of reperfusion. Trolox could prevent oxidative stress-induced apoptosis in thymocytes. Pre- or posttreatment of cells with Trolox reduced H2O2-induced DNA fragmentation to control levels and below.

Chemical Information
Molecular Weight 250.29
Formula C14H18O4
CAS Number 53188-07-1
Solubility (25°C) DMSO ≥ 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Beckers, et al. Anal Biochem. Characterization of gonadotropin-releasing hormone analogs based on a sensitive cellular luciferase reporter gene assay.

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Keywords: Trolox supplier, ROS, inhibitors, activators

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