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Triglycidyl Isocyanurate (Teroxirone)

Cat. No. M20697

All AbMole products are for research use only, cannot be used for human consumption.

Triglycidyl Isocyanurate (Teroxirone) Structure
Synonym:

Tris(2,3-epoxypropyl) Isocyanurate, TGI, TGIC

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Quality Control & Documentation
Biological Activity

Triglycidyl Isocyanurate, also known as Teroxirone, is a triazene triepoxide with antineoplastic activity. It inhibits growth of human non-small cell lung cancer cells by activating p53. Triglycidyl Isocyanurate alkylates and cross-links DNA, thereby inhibiting DNA replication. Triglycidyl Isocyanurate is also used in various polyester powder coatings in the metal finishing industry.

Chemical Information
Molecular Weight 297.26
Formula C12H15N3O6
CAS Number 2451-62-9
Solubility (25°C) DMSO 59 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Anna Jeżewska, et al. Int J Environ Res Public Health. Determination of Triglycidyl Isocyanurate in Workplace Air

[2] Seung-Hun Kim, et al. Biomed Pharmacother. Teroxirone suppresses growth and motility of human hepatocellular carcinoma cells

[3] Jing-Ping Wang, et al. Toxicol Appl Pharmacol. Teroxirone inhibited growth of human non-small cell lung cancer cells by activating p53

[4] W Anees, et al. Occup Med (Lond). Occupational asthma caused by heated triglycidyl isocyanurate

[5] Joaqun Sastre, et al. Int Arch Occup Environ Health. Occupational asthma caused by triglycidyl isocyanurate

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  Catalog
Abmole Inhibitor Catalog




Keywords: Triglycidyl Isocyanurate (Teroxirone), Tris(2,3-epoxypropyl) Isocyanurate, TGI, TGIC supplier, p53, inhibitors, activators

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