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TPI-287 

Cat. No. M30686

All AbMole products are for research use only, cannot be used for human consumption.

TPI-287  Structure
Synonym:

Abeotaxane

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Quality Control & Documentation
Biological Activity

TPI-287, a blood-brain barrier-permeable microtubule stabilizer, can significantly reduce metastatic colonization of breast cancer in the brain.

Chemical Information
Molecular Weight 869.99
Formula C46H63NO15
CAS Number 849213-15-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Müge Sak, et al. Cancer Chemother Pharmacol. The CNS-penetrating taxane drug TPI 287 potentiates antiglioma activity of the AURKA inhibitor alisertib in vivo

[2] Cory T Zumbar, et al. J Neurooncol. The CNS penetrating taxane TPI 287 and the AURKA inhibitor alisertib induce synergistic apoptosis in glioblastoma cells

[3] Daniel P Fitzgerald, et al. Mol Cancer Ther. TPI-287, a new taxane family member, reduces the brain metastatic colonization of breast cancer cells

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  Catalog
Abmole Inhibitor Catalog




Keywords: TPI-287 , Abeotaxane supplier, Microtubule, inhibitors, activators

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