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TP0472993 is a novel, orally active, selective inhibitor of 20-hydroxyeicosatetraenoic acid (20-HETE) synthesis that inhibits the production of 20-HETE, thereby reducing the ERK1/2 and STAT3 signaling pathways, and ultimately inhibiting the progression of renal fibrosis. It can be used in studies related to chronic kidney disease (CKD).
| Molecular Weight | 300.36 |
| Formula | C16H20N4O2 |
| CAS Number | 2126874-77-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 25 mg/mL |
| Storage | 4°C, protect from light |
| Related Cytochrome P450 (e.g. CYP17) Products |
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| MS-PPOH
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| (3S,5S)-Atorvastatin sodium salt
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