Certificate of Analysis

 

Product Name: TP0472993
Catalog Number: M40620
CAS Number: 2126874-77-7

Physical and Chemical Properties
Formula: C16H20N4O2
Molecular Weight: 300.36
Form: Solid
Solubility: DMSO 25 mg/mL
Storage: 4°C, protect from light
Chemical Structure: TP0472993  Structure
Analytical Data
QC Standard: >98.5%
H-NMR: Consistent with structure
Product Information
Description: TP0472993 is a novel, orally active, selective inhibitor of 20-hydroxyeicosatetraenoic acid (20-HETE) synthesis that inhibits the production of 20-HETE, thereby reducing the ERK1/2 and STAT3 signaling pathways, and ultimately inhibiting the progression of renal fibrosis. It can be used in studies related to chronic kidney disease (CKD).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.