Free shipping on all orders over $ 500

Tetrahydromagnolol

Cat. No. M18475
Tetrahydromagnolol Structure
Size Price Availability Quantity
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Tetrahydromagnolol

Chemical Information
CAS Number 20601-85-8
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Jing Li, et al. ACS Chem Neurosci. Zebrafish-Based Screening of Antiseizure Plants Used in Traditional Chinese Medicine: Magnolia officinalis Extract and Its Constituents Magnolol and Honokiol Exhibit Potent Anticonvulsant Activity in a Therapy-Resistant Epilepsy Model

[2] Fabrizio Schifano, et al. Hum Psychopharmacol. Is there a potential of misuse for Magnolia officinalis compounds/metabolites?

[3] Viktor Rempel, et al. ACS Med Chem Lett. Magnolia Extract, Magnolol, and Metabolites: Activation of Cannabinoid CB2 Receptors and Blockade of the Related GPR55

[4] Alexander Fuchs, et al. PLoS One. The natural product magnolol as a lead structure for the development of potent cannabinoid receptor agonists

Related Others Products
Lutonarin

Lutonarin is a antioxidant agent that can be isolated from green barley leaves. Lutonarin (Isoorientin 7-O-glucoside) is a natural product found in aerial part of Silene jeniseensis.

Ethyl glucoside

Ethyl glucoside is a kind of phenolic compound. Ethyl β-D-glucopyranoside can be isolated from ethanolic extract of Scabiosa stellata LS.

Methyl 2,4-dihydroxyphenylacetate

Methyl 2,4-dihydroxyphenylacetate is a natural product isolated from Nigella damascena seeds with selective phytotoxic effects.

Magnesium Lithospermate B

Magnesium Lithospermate B is a derivative of caffeic acid tetramer extracted from Salviae miltiorrhizae. Magnesium Lithospermate B is widely used for the research of cardiovascular diseases, and it can protect against glucose-induced intracellular oxidative damage. Magnesium Lithospermate B also suppresses neuroinflammation and attenuates neurodegeneration.

5-O-Methylvisamminol

5-O-Methylvisamminol, a (furo) chromone identified in the extract of T. glauca. 5-O-Methylvisamminol is useful in (chemical) phylogeny and is a possible excellent chemotaxonomic marker for Apiaceae.

  Catalog
Abmole Inhibitor Catalog




Keywords: Tetrahydromagnolol supplier, Others, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.