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Tapotoclax

Cat. No. M13380

All AbMole products are for research use only, cannot be used for human consumption.

Tapotoclax Structure
Synonym:

AMG-176;CS-2836

Size Price Availability Quantity
1mg USD 680  USD680 In stock
5mg USD 1950  USD1950 In stock
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Quality Control & Documentation
Biological Activity

Tapotoclax is an inhibitor of myeloid leukemia cell differentiation protein McL-1 (myeloid leukemia-1) with a Ki value of 0.13 nM and has potential pro-apoptotic and anti-tumor activity.

Chemical Information
Molecular Weight 613.21
Formula C33H41ClN2O5S
CAS Number 1883727-34-1
Solubility (25°C) DMSO ≥ 40 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Xue Yi, et al. Clin Cancer Res. AMG-176, an Mcl-1 Antagonist, Shows Preclinical Efficacy in Chronic Lymphocytic Leukemia

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  Catalog
Abmole Inhibitor Catalog




Keywords: Tapotoclax, AMG-176;CS-2836 supplier, Bcl-2, inhibitors, activators

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