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TAK-418 is a selective, orally active LSD1 (KDM1A) enzyme inhibitor with an IC50 of 2.9 nM. It is an orally administered CNS-permeable clinical candidate for the study of neurodevelopmental disorders, such as autism spectrum disorders.
| Molecular Weight | 356.91 |
| Formula | C17H25ClN2O2S |
| CAS Number | 1818252-53-7 |
| Solubility (25°C) | DMSO : 55 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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