All AbMole products are for research use only, cannot be used for human consumption.
SX-682 is an orally bioavailable, potent and selective CXCR1/2 allosteric inhibitor, it may be useful for castration-resistant prostate cancer. SX-682 can block tumor myeloid-derived suppressor cells (MDSCs) recruitment and enhance T cell activation and antitumor immunity. CXCR1 and CXCR2 chemokine receptors and their ligands (CXCL1/2/3/7/8) play an important role in tumor progression.
| Molecular Weight | 467.2 |
| Formula | C19H14BF4N3O4S |
| CAS Number | 1648843-04-2 |
| Solubility (25°C) | DMSO ≥ 120 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related CXCR Products |
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| Elubrixin
Elubrixin (SB-656933) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. |
| VUF 11222
VUF 11222 is a CXCR3 non-peptide-like agonist. |
| (±)-AMG 487
(±)-AMG 487 is a racemate of AMG 487. |
| Elubrixin tosylate
Elubrixin tosylate (SB-656933 tosylate) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. |
| Elubrixin hydrochloride
Elubrixin (SB-656933) hydrochloride is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. |
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Products are for research use only. Not for human use. We do not sell to patients.
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