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Surfactin is a lipopeptide antibiotic that is composed of one β-hydroxy fatty acid, used as a surfactant to mediate flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes, also used as adjuvant. It is a powerful biosurfactant that causes lysis of erythrocytes and bacteria. It is also a clotting inhibitor. Surfactin is thought to disrupt or disintegrate membranes via physicochemical interaction with the membranes.
| Molecular Weight | 1036.34 |
| Formula | C53H93N7O13 |
| CAS Number | 24730-31-2 |
| Solubility (25°C) | Water 20 mg/mL DMSO 30 mg/mL |
| Storage | 2-8°C, dry, sealed |
| Related Adjuvants Products |
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| Schizophyllan
Schizophyllan, a β-D-glucan derived from Schizophyllan, activates Tc cells, NK cells, macrophages, as well as promotes the secretion of various lymphokines such as IL-1, IL-2, IL-3, IFN. It can be used as an immune adjuvant with potential immunomodulatory and antitumor activities. |
| Aluminum Phosphate
Aluminum Phosphate is a widely used adjuvant and has been shown to increase the excretion rate of strontium for use in studies related to vaccines and gastrointestinal diseases. |
| Peptidoglycan
The peptidoglycan (murein) sacculus is a unique and essential structural element in the cell wall of most bacteria. This product is extracted from Bacillus subtilis. |
| QS-21
QS-21, an immunostimulatory saponin, could be used as a potent vaccine adjuvant. QS-21 stimulates Th2 humoral and Th1 cell-mediated immune responses through action on antigen presenting cells (APCs) and T cells. QS-21 can activate the NLRP3 inflammasome with subsequent release of caspase-1 dependent cytokines, IL-1β and IL-18. |
| Polygalasaponin XXXI
Polygalasaponin XXXI (Onjisaponin F) is an effective adjuvant for intranasal administration of influenza Influenza hemagglutinin (HA) vaccine. |
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