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STING agonist-3

Cat. No. M14124

All AbMole products are for research use only, cannot be used for human consumption.

STING agonist-3 Structure

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Quality Control & Documentation
Biological Activity

STING agonist-3 is a selective and non-nucleotide small-molecule STING agonist with a pEC50 and pIC50 of 7.5 and 9.5, respectively. STING agonist-3 has durable anti-tumor effect and tremendous potential to improve treatment of cancer.

Chemical Information
Molecular Weight 750.81
CAS Number 2138299-29-1
Solubility (25°C) DMSO 40 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ru-Yan Zhang, et al. A protein vaccine with Alum/c-GAMP/poly(I:C) rapidly boosts robust immunity against SARS-CoV-2 and variants of concern

[2] Markta Pimkov Polidarov, et al. Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3',3'-c-Di(2'F,2'dAMP)

[3] Michael A Collier, et al. Acetalated Dextran Microparticles for Codelivery of STING and TLR7/8 Agonists

[4] Chih-Hang Anthony Tang, et al. Agonist-Mediated Activation of STING Induces Apoptosis in Malignant B Cells

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Keywords: STING agonist-3 supplier, STING, inhibitors, activators

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